HitPredict

Interactor 1: RAC1 (P63001)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (p21-Rac1)
Gene: RAC1

Interactor 2: MK09 (Q9WTU6)
Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC 2.7.11.24) (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2)
Gene: Mapk9

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	18423204
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Pkinase~Ras
Common GO terms	GO:0001934 - positive regulation of protein phosphorylation GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 192 Mm			1 423
+	Hs
		800742 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		MK08_HUMAN (1-423): 4.71e-156: 449: 81.27
+	Hs
		800740 CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31		MK08_HUMAN (1-423): 4.71e-156: 449: 81.27
+	Mm
		925813 RAC1_MOUSE (1-192): 3.81e-86: 253: 100.00		MK08_MOUSE (1-378): 8.57e-149: 429: 84.39
+	Hs
		800741 RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98		MK08_HUMAN (1-423): 4.71e-156: 449: 81.27
+	Hs
		625333 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		CDK2_HUMAN (23-329): 1.48e-138: 400: 33.87
+	Hs
		436162 RHOC_HUMAN (5-192): 8.68e-75: 224: 57.45		CDK2_HUMAN (23-329): 1.48e-138: 400: 33.87
+	Rn
		926512 RAC1_RAT (1-192): 3.81e-86: 253: 100.00		MK01_RAT (15-364): 8.44e-86: 267: 41.06