HitPredict

Interactor 1: LIS1 (P63005)
Platelet-activating factor acetylhydrolase IB subunit beta (Lissencephaly-1 protein) (LIS-1) (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha)
Gene: Pafah1b1

Interactor 2: Q155P7 (Q155P7)
LEK1
Gene: Cenpf

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.30	0.60	0.428

Property	Details
Experiments	15939891
Identification Methods	confocal microscopy
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000776 - kinetochore GO:0005737 - cytoplasm GO:0005813 - centrosome GO:0008017 - microtubule binding GO:0048471 - perinuclear region of cytoplasm and 1 others more... GO:0070840 - dynein complex binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 410 Mm			1 2997
+	Hs
		792973 LIS1_HUMAN (1-410): 7.99e-138: 401: 99.76		CENPE_HUMAN (1-1181): 2.7e-36: 154: 11.38
+	Hs
		551632 LIS1_HUMAN (1-410): 7.99e-138: 401: 99.76		DESP_HUMAN (4-886): 5.9e-20: 100: 12.84
+	Hs
		724952 FBXW7_HUMAN (51-403): 1.97e-85: 276: 25.14		MYH9_HUMAN (1-889): 3.64e-37: 157: 12.82
+	Hs
		1281478 FBXW7_HUMAN (51-403): 1.97e-85: 276: 25.14		MACF1_HUMAN (12-2227): 3.52e-25: 118: 8.82
+	Hs
		725215 FBXW7_HUMAN (51-403): 1.97e-85: 276: 25.14		MYH10_HUMAN (2514-2993): 1.22e-18: 96.2: 9.73
+	Hs
		903607 WDR5_HUMAN (4-323): 3.59e-73: 233: 25.38		MACF1_HUMAN (12-2227): 3.52e-25: 118: 8.82
+	Hs
		551655 WDR5_HUMAN (4-323): 3.59e-73: 233: 25.38		DESP_HUMAN (4-886): 5.9e-20: 100: 12.84
+	Hs
		724753 GBB2_HUMAN (166-410): 5.38e-51: 176: 20.48		MYH9_HUMAN (1-889): 3.64e-37: 157: 12.82
+	Hs
		551766 WDR5B_HUMAN (4-323): 6.99e-73: 232: 26.30		DESP_HUMAN (4-886): 5.9e-20: 100: 12.84
+	Hs
		903233 WDR5_HUMAN (4-323): 3.59e-73: 233: 25.38		GOGB1_HUMAN (2267-2993): 3.81e-15: 85: 10.04
+	Hs
		728492 POC1A_HUMAN (180-410): 4.01e-66: 217: 30.30		MYH11_HUMAN (3-500): 2.7e-16: 88.5: 14.14
+	Hs
		148610 WDR5_HUMAN (4-323): 3.59e-73: 233: 25.38		CTRO_HUMAN (1117-1994): 1.59e-10: 69.7: 13.87
+	Hs
		551659 GBB2_HUMAN (166-410): 5.38e-51: 176: 20.48		DESP_HUMAN (4-886): 5.9e-20: 100: 12.84
+	Hs
		551854 NLE1_HUMAN (3-177): 1.58e-33: 132: 18.75		DESP_HUMAN (4-886): 5.9e-20: 100: 12.84
+	Hs
		148168 PLRG1_HUMAN (224-409): 1.51e-43: 160: 24.73		CTRO_HUMAN (1117-1994): 1.59e-10: 69.7: 13.87
+	Hs
		197084 PRP4_HUMAN (10-177): 3.12e-27: 115: 20.59		CP250_HUMAN (1-851): 1.12e-23: 113: 11.73
+	Hs
		148157 PRP4_HUMAN (10-177): 3.12e-27: 115: 20.59		CTRO_HUMAN (1117-1994): 1.59e-10: 69.7: 13.87
+	Hs
		149156 SNR40_HUMAN (328-408): 4.84e-18: 86.8: 26.83		CTRO_HUMAN (1117-1994): 1.59e-10: 69.7: 13.87
+	Hs
		148658 RACK1_HUMAN (103-261): 2.4e-16: 81.3: 33.13		CTRO_HUMAN (1117-1994): 1.59e-10: 69.7: 13.87