HitPredict

Interactor 1: AP2B1 (P63010)
AP-2 complex subunit beta (AP105B) (Adaptor protein complex AP-2 subunit beta) (Adaptor-related protein complex 2 subunit beta) (Beta-2-adaptin) (Beta-adaptin) (Clathrin assembly protein complex 2 beta large chain) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit)
Gene: AP2B1

Interactor 2: OCRL (Q01968)
Inositol polyphosphate 5-phosphatase OCRL (EC 3.1.3.36) (EC 3.1.3.56) (Inositol polyphosphate 5-phosphatase OCRL-1) (OCRL-1) (Lowe oculocerebrorenal syndrome protein) (Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase) (EC 3.1.3.86)
Gene: OCRL

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	27173435, 25107275
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 937 Hs			1 901
+	Hs
		968133 AP1B1_HUMAN (1-937): 0: 888: 82.72		OCRL_HUMAN (1-901): 0: 1075: 100.00
+	Hs
		321531 AP2A1_HUMAN (11-932): 0: 634: 16.97		OCRL_HUMAN (1-901): 0: 1075: 100.00
+	Hs
		302140 AP2A2_HUMAN (11-933): 0: 600: 16.99		OCRL_HUMAN (1-901): 0: 1075: 100.00
+	Hs
		212621 AP1G1_HUMAN (11-808): 1.03e-173: 527: 17.57		OCRL_HUMAN (1-901): 0: 1075: 100.00
+	Hs
		203219 AP2B1_HUMAN (1-937): 0: 926: 100.00		SYNJ1_HUMAN (218-733): 8.18e-121: 403: 24.37
+	Hs
		203223 AP1B1_HUMAN (1-937): 0: 888: 82.72		SYNJ1_HUMAN (218-733): 8.18e-121: 403: 24.37
+	Hs
		203194 AP2A1_HUMAN (11-932): 0: 634: 16.97		SYNJ1_HUMAN (218-733): 8.18e-121: 403: 24.37
+	Rn
		1144064 Q66HM2_RAT (11-932): 0: 590: 16.38		SYNJ1_RAT (218-738): 2.76e-120: 401: 24.79
+	Sc
		730448 AP1B1_YEAST (12-697): 3.62e-180: 540: 35.84		INP53_YEAST (215-556): 1.77e-110: 367: 30.75