HitPredict

Interactor 1: AP2B1 (P63010)
AP-2 complex subunit beta (AP105B) (Adaptor protein complex AP-2 subunit beta) (Adaptor-related protein complex 2 subunit beta) (Beta-2-adaptin) (Beta-adaptin) (Clathrin assembly protein complex 2 beta large chain) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit)
Gene: AP2B1

Interactor 2: DYR1A (Q13627)
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.11.23) (EC 2.7.12.1) (Dual specificity YAK1-related kinase) (HP86) (Protein kinase minibrain homolog) (MNBH) (hMNB)
Gene: DYRK1A

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.50	0.521

Property	Details
Experiments	30979931, 36950384
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 937 Hs			1 763
+	Hs
		321542 AP2A1_HUMAN (11-932): 0: 634: 16.97		DYR1A_HUMAN (1-763): 0: 613: 100.00
+	Hs
		625396 AP1B1_HUMAN (1-937): 0: 888: 82.72		CDK2_HUMAN (156-420): 1.05e-117: 358: 26.85
+	Hs
		302147 AP2A2_HUMAN (11-933): 0: 600: 16.99		DYR1A_HUMAN (1-763): 0: 613: 100.00
+	Hs
		119964 AP3B1_HUMAN (8-594): 5.76e-178: 547: 28.17		DYR1A_HUMAN (1-763): 0: 613: 100.00
+	Hs
		625261 COPB_HUMAN (8-927): 0: 561: 12.47		CDK2_HUMAN (156-420): 1.05e-117: 358: 26.85
+	Ce
		1094943 Q22601_CAEEL (9-626): 7.54e-140: 442: 20.26		MBK1_CAEEL (6-531): 1.33e-120: 385: 49.91