HitPredict

Interactor 1: AP2B1 (P63010)
AP-2 complex subunit beta (AP105B) (Adaptor protein complex AP-2 subunit beta) (Adaptor-related protein complex 2 subunit beta) (Beta-2-adaptin) (Beta-adaptin) (Clathrin assembly protein complex 2 beta large chain) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit)
Gene: AP2B1

Interactor 2: AP1M1 (Q9BXS5)
AP-1 complex subunit mu-1 (AP-mu chain family member mu1A) (Adaptor protein complex AP-1 subunit mu-1) (Adaptor-related protein complex 1 subunit mu-1) (Clathrin assembly protein complex 1 mu-1 medium chain 1) (Clathrin coat assembly protein AP47) (Clathrin coat-associated protein AP47) (Golgi adaptor HA1/AP1 adaptin mu-1 subunit) (Mu-adaptin 1) (Mu1A-adaptin)
Gene: AP1M1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.896

The method score is based on:

Property Details
Experiments 16189514, 34079125, 33961781, 9341158
Identification Methods two hybrid, proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid pooling approach
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Adap_comp_sub~Adaptin_N, Adaptin_N~Clat_adaptor_s
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006886 - intracellular protein transport
GO:0016020 - membrane
GO:0016192 - vesicle-mediated transport
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 937
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024