HitPredict

Interactor 1: RAB3A (P63011)
Ras-related protein Rab-3A
Gene: RAB3A

Interactor 2: RAB4B (Q91ZR1)
Ras-related protein Rab-4B (EC 3.6.5.2)
Gene: RAB4B

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	26885862
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005886 - plasma membrane GO:0030672 - synaptic vesicle membrane GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 220 Mm			1 213
+	Hs
		918879 RB11B_HUMAN (12-217): 2.55e-99: 288: 37.86		RAB1A_HUMAN (1-211): 3.21e-87: 257: 40.28
+	Hs
		1079964 RB11B_HUMAN (12-217): 2.55e-99: 288: 37.86		RAB1B_HUMAN (1-211): 1.77e-86: 255: 39.81
+	Hs
		914093 RB11B_HUMAN (12-217): 2.55e-99: 288: 37.86		RB11A_HUMAN (2-211): 5.1e-86: 255: 44.29
+	Mm
		919023 RAB3C_MOUSE (1-220): 4.19e-93: 273: 83.18		RAB1B_MOUSE (1-211): 9.57e-87: 256: 39.81
+	Zm
		73944 B4FAE1_MAIZE (15-219): 6.1e-89: 262: 45.37		B4FAE1_MAIZE (1-212): 9.51e-90: 264: 40.85
+	Hs
		591537 RAB3B_HUMAN (1-220): 7.54e-90: 265: 77.27		RAB2A_HUMAN (4-192): 2.82e-88: 260: 55.03
+	Hs
		591801 RAB1A_HUMAN (12-220): 7.94e-89: 262: 43.54		RAB4A_HUMAN (1-213): 1.11e-88: 261: 86.85
+	Hs
		591540 RAB3B_HUMAN (1-220): 7.54e-90: 265: 77.27		RAB1A_HUMAN (1-211): 3.21e-87: 257: 40.28
+	Hs
		895026 RAB1A_HUMAN (12-220): 7.94e-89: 262: 43.54		RAB2A_HUMAN (4-192): 2.82e-88: 260: 55.03
+	Hs
		591538 RAB3B_HUMAN (1-220): 7.54e-90: 265: 77.27		RB11A_HUMAN (2-211): 5.1e-86: 255: 44.29
+	Hs
		918846 RAB1A_HUMAN (12-220): 7.94e-89: 262: 43.54		RAB1A_HUMAN (1-211): 3.21e-87: 257: 40.28
+	Hs
		918916 RAB1A_HUMAN (12-220): 7.94e-89: 262: 43.54		RAB2B_HUMAN (4-211): 8.45e-87: 257: 51.63
+	Mm
		919000 RAB1A_MOUSE (12-220): 7.94e-89: 262: 43.54		RAB1B_MOUSE (1-211): 9.57e-87: 256: 39.81
+	Hs
		591578 RAB3B_HUMAN (1-220): 7.54e-90: 265: 77.27		RB11B_HUMAN (2-211): 5.98e-85: 252: 44.08
+	Hs
		913992 RAB1A_HUMAN (12-220): 7.94e-89: 262: 43.54		RB11A_HUMAN (2-211): 5.1e-86: 255: 44.29
+	Hs
		918944 RAB1A_HUMAN (12-220): 7.94e-89: 262: 43.54		RAB1B_HUMAN (1-211): 1.77e-86: 255: 39.81
+	Hs
		895264 RAB1B_HUMAN (15-220): 1.2e-86: 256: 42.23		RAB2A_HUMAN (4-192): 2.82e-88: 260: 55.03
+	Hs
		896605 RAB1A_HUMAN (12-220): 7.94e-89: 262: 43.54		RAB14_HUMAN (4-213): 1.21e-85: 254: 58.10
+	Hs
		896681 RAB1B_HUMAN (15-220): 1.2e-86: 256: 42.23		RAB14_HUMAN (4-213): 1.21e-85: 254: 58.10