HitPredict

Interactor 1: HSP7C (P63018)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8)
Gene: Hspa8

Interactor 2: GRB7 (Q9QZC5)
Growth factor receptor-bound protein 7 (Epidermal growth factor receptor GRB-7) (GRB7 adapter protein)
Gene: GRB7

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32360748
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 646 Rn			1 535
+	Hs
		504078 HSP7C_HUMAN (1-646): 0: 973: 99.85		GRB7_HUMAN (1-535): 0: 587: 90.11
+	Hs
		504021 HSP7C_HUMAN (1-646): 0: 973: 99.85		GRB10_HUMAN (1-535): 0: 555: 52.88
+	Hs
		564069 HSP76_HUMAN (6-646): 0: 960: 77.54		GRB10_HUMAN (1-535): 0: 555: 52.88
+	Hs
		503732 HSP7C_HUMAN (1-646): 0: 973: 99.85		VAV2_HUMAN (85-529): 4.68e-77: 261: 13.68
+	Hs
		503720 HSP7C_HUMAN (1-646): 0: 973: 99.85		BMX_HUMAN (223-534): 2.07e-49: 182: 16.39
+	Hs
		411570 HSP7C_HUMAN (1-646): 0: 973: 99.85		LCK_HUMAN (320-530): 7.02e-46: 170: 20.87
+	Hs
		411965 HSP7C_HUMAN (1-646): 0: 973: 99.85		FYN_HUMAN (372-532): 1.7e-45: 169: 19.05
+	Hs
		433227 HSP7C_HUMAN (1-646): 0: 973: 99.85		YES_HUMAN (372-533): 8.44e-45: 167: 20.12
+	Hs
		442767 HSP7C_HUMAN (1-646): 0: 973: 99.85		HCK_HUMAN (379-530): 1.22e-44: 166: 21.52
+	Hs
		503340 HSP7C_HUMAN (1-646): 0: 973: 99.85		SRC_HUMAN (360-531): 2.51e-41: 158: 22.91
+	Hs
		411586 HSP76_HUMAN (6-646): 0: 960: 77.54		LCK_HUMAN (320-530): 7.02e-46: 170: 20.87
+	Hs
		442775 HSP76_HUMAN (6-646): 0: 960: 77.54		HCK_HUMAN (379-530): 1.22e-44: 166: 21.52
+	Hs
		503596 HSP7C_HUMAN (1-646): 0: 973: 99.85		CSK_HUMAN (397-528): 1.44e-29: 122: 28.26
+	Hs
		564025 HSP76_HUMAN (6-646): 0: 960: 77.54		CSK_HUMAN (397-528): 1.44e-29: 122: 28.26
+	Gg
		94427 HSP70_CHICK (3-646): 0: 975: 86.07		KSYK_CHICK (426-532): 1.16e-12: 72.5: 33.65
+	Hs
		503853 HSP7C_HUMAN (1-646): 0: 973: 99.85		GRB2_HUMAN (400-516): 2.34e-14: 74: 27.35
+	Hs
		713938 HS71L_HUMAN (2-646): 0: 971: 82.64		GRB2_HUMAN (400-516): 2.34e-14: 74: 27.35
+	Hs
		503950 HSP7C_HUMAN (1-646): 0: 973: 99.85		PTN11_HUMAN (431-522): 2.09e-11: 68.3: 34.78
+	Gg
		94419 HSP7C_CHICK (1-646): 0: 967: 97.83		KSYK_CHICK (426-532): 1.16e-12: 72.5: 33.65
+	Hs
		483751 HS71A_HUMAN (1-646): 0: 953: 84.52		KSYK_HUMAN (421-528): 5.74e-12: 70.2: 32.41