HitPredict

Interactor 1: VAMP2 (P63027)
Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2)
Gene: VAMP2

Interactor 2: RHOG (P84095)
Rho-related GTP-binding protein RhoG
Gene: RHOG

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0030667 - secretory granule membrane GO:0031410 - cytoplasmic vesicle
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 116 Hs			1 191
+	Hs
		850556 VAMP7_HUMAN (3-96): 2.69e-30: 109: 31.31		RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88
+	Hs
		850558 VAMP7_HUMAN (3-96): 2.69e-30: 109: 31.31		RHOG_HUMAN (1-191): 9.12e-82: 242: 100.00
+	Hs
		545275 VAMP7_HUMAN (3-96): 2.69e-30: 109: 31.31		RAC2_HUMAN (1-191): 1.28e-78: 234: 71.35
+	Hs
		850550 VAMP7_HUMAN (3-96): 2.69e-30: 109: 31.31		CDC42_HUMAN (1-191): 1.3e-78: 234: 60.73
+	Hs
		850552 VAMP7_HUMAN (3-96): 2.69e-30: 109: 31.31		RHOA_HUMAN (5-191): 1.26e-78: 234: 55.62
+	Hs
		436215 VAMP7_HUMAN (3-96): 2.69e-30: 109: 31.31		RHOC_HUMAN (5-191): 8.34e-77: 230: 56.15
+	Hs
		925171 VAMP2_HUMAN (25-116): 9.9e-26: 94.7: 100.00		RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88
+	Hs
		263218 SC22B_HUMAN (1-115): 4.12e-24: 93.2: 17.09		RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88
+	Hs
		850548 VAMP7_HUMAN (3-96): 2.69e-30: 109: 31.31		RAC3_HUMAN (1-177): 1.67e-75: 226: 72.88
+	Hs
		564456 VAMP7_HUMAN (3-96): 2.69e-30: 109: 31.31		RHOQ_HUMAN (4-189): 5.74e-73: 220: 56.84
+	Hs
		545311 VAMP2_HUMAN (25-116): 9.9e-26: 94.7: 100.00		RAC2_HUMAN (1-191): 1.28e-78: 234: 71.35
+	Mm
		892719 VAMP2_MOUSE (25-116): 9.9e-26: 94.7: 100.00		CDC42_MOUSE (1-191): 1.3e-78: 234: 60.73
+	Hs
		893880 VAMP2_HUMAN (25-116): 9.9e-26: 94.7: 100.00		CDC42_HUMAN (1-191): 1.3e-78: 234: 60.73
+	Hs
		900359 VAMP2_HUMAN (25-116): 9.9e-26: 94.7: 100.00		RHOA_HUMAN (5-191): 1.26e-78: 234: 55.62
+	Hs
		263159 SC22B_HUMAN (1-115): 4.12e-24: 93.2: 17.09		RAC2_HUMAN (1-191): 1.28e-78: 234: 71.35
+	Hs
		263210 SC22B_HUMAN (1-115): 4.12e-24: 93.2: 17.09		CDC42_HUMAN (1-191): 1.3e-78: 234: 60.73
+	Hs
		263212 SC22B_HUMAN (1-115): 4.12e-24: 93.2: 17.09		RHOA_HUMAN (5-191): 1.26e-78: 234: 55.62
+	Hs
		436247 VAMP2_HUMAN (25-116): 9.9e-26: 94.7: 100.00		RHOC_HUMAN (5-191): 8.34e-77: 230: 56.15
+	Hs
		263146 SC22B_HUMAN (1-115): 4.12e-24: 93.2: 17.09		RHOC_HUMAN (5-191): 8.34e-77: 230: 56.15
+	Hs
		263209 SC22B_HUMAN (1-115): 4.12e-24: 93.2: 17.09		RAC3_HUMAN (1-177): 1.67e-75: 226: 72.88