HitPredict

Interactor 1: VAMP2 (P63027)
Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2)
Gene: VAMP2

Interactor 2: RB11B (Q15907)
Ras-related protein Rab-11B (EC 3.6.5.2) (GTP-binding protein YPT3)
Gene: RAB11B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0008021 - synaptic vesicle GO:0030672 - synaptic vesicle membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 116 Hs			1 218
+	Hs
		850554 VAMP7_HUMAN (3-96): 2.69e-30: 109: 31.31		RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37
+	Hs
		1079324 VAMP3_HUMAN (26-98): 7.88e-25: 92: 91.78		RB11B_HUMAN (1-218): 2.77e-95: 278: 100.00
+	Hs
		1079958 VAMP8_HUMAN (20-99): 2.06e-24: 90.9: 32.50		RB11B_HUMAN (1-218): 2.77e-95: 278: 100.00
+	Hs
		261649 VAMP4_HUMAN (18-99): 1.04e-26: 97.8: 35.37		RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37
+	Hs
		913996 VAMP2_HUMAN (25-116): 9.9e-26: 94.7: 100.00		RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37
+	Hs
		263215 SC22B_HUMAN (1-115): 4.12e-24: 93.2: 17.09		RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37
+	Hs
		180855 YKT6_HUMAN (5-85): 5.79e-24: 92.4: 24.69		RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37
+	Hs
		914092 VAMP3_HUMAN (26-98): 7.88e-25: 92: 91.78		RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37
+	Hs
		914322 VAMP8_HUMAN (20-99): 2.06e-24: 90.9: 32.50		RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37
+	Hs
		918878 VAMP3_HUMAN (26-98): 7.88e-25: 92: 91.78		RAB1A_HUMAN (1-215): 2.92e-90: 265: 43.26
+	Hs
		87580 C9JXZ5_HUMAN (46-99): 8.01e-21: 80.9: 37.04		RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37
+	Hs
		1079428 VAMP3_HUMAN (26-98): 7.88e-25: 92: 91.78		RAB1B_HUMAN (4-215): 8.36e-87: 256: 44.81
+	Hs
		180846 YKT6_HUMAN (5-85): 5.79e-24: 92.4: 24.69		RAB25_HUMAN (2-218): 1.3e-83: 249: 60.63
+	Hs
		884499 VAMP3_HUMAN (26-98): 7.88e-25: 92: 91.78		RAB25_HUMAN (2-218): 1.3e-83: 249: 60.63
+	Hs
		850551 VAMP7_HUMAN (3-96): 2.69e-30: 109: 31.31		RAB2A_HUMAN (8-178): 5.89e-61: 191: 55.56
+	Hs
		261647 VAMP4_HUMAN (18-99): 1.04e-26: 97.8: 35.37		RAB2A_HUMAN (8-178): 5.89e-61: 191: 55.56
+	Hs
		895029 VAMP2_HUMAN (25-116): 9.9e-26: 94.7: 100.00		RAB2A_HUMAN (8-178): 5.89e-61: 191: 55.56
+	Hs
		263211 SC22B_HUMAN (1-115): 4.12e-24: 93.2: 17.09		RAB2A_HUMAN (8-178): 5.89e-61: 191: 55.56
+	Hs
		180851 YKT6_HUMAN (5-85): 5.79e-24: 92.4: 24.69		RAB2A_HUMAN (8-178): 5.89e-61: 191: 55.56
+	Hs
		895094 VAMP3_HUMAN (26-98): 7.88e-25: 92: 91.78		RAB2A_HUMAN (8-178): 5.89e-61: 191: 55.56