HitPredict

Interactor 1: MK01 (P63086)
Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2)
Gene: Mapk1

Interactor 2: SRSF5 (Q09167)
Serine/arginine-rich splicing factor 5 (Delayed-early protein HRS) (Insulin-induced growth response protein CL-4) (Pre-mRNA-splicing factor SRP40) (Splicing factor, arginine/serine-rich 5)
Gene: SRSF5

Species: Rattus norvegicus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30053369
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 358 Rn			1 269
+	Rn
		102586 MK03_RAT (13-355): 4.12e-153: 437: 88.34		G3V9N0_RAT (98-189): 2.31e-17: 83.5: 20.62
+	Rn
		600488 MK03_RAT (13-355): 4.12e-153: 437: 88.34		PABP1_RAT (98-189): 4.35e-17: 82.4: 17.53
+	Mm
		857304 MK01_MOUSE (1-358): 3.67e-159: 451: 100.00		TIA1_MOUSE (2-100): 5.9e-12: 67: 15.84
+	Rn
		78186 MK03_RAT (13-355): 4.12e-153: 437: 88.34		B5DF80_RAT (98-189): 3.23e-16: 80.1: 16.50
+	Hs
		658891 MK01_HUMAN (9-358): 5.56e-158: 448: 99.71		TIAR_HUMAN (3-103): 1.3e-12: 68.9: 14.56
+	Hs
		647674 MK03_HUMAN (3-356): 7.99e-154: 439: 85.88		RBM4_HUMAN (3-122): 9.02e-16: 77.7: 22.50
+	Hs
		647544 MK03_HUMAN (3-356): 7.99e-154: 439: 85.88		TIAR_HUMAN (3-103): 1.3e-12: 68.9: 14.56
+	Hs
		1028672 MK14_HUMAN (16-354): 1.6e-111: 330: 48.97		SRSF5_HUMAN (1-179): 1.44e-51: 171: 100.00