Interactor 1: MK01 (P63086)
Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2)
Gene: Mapk1
Interactor 2: DCC (Q63155)
Netrin receptor DCC (Tumor suppressor protein DCC)
Gene: DCC
Species: Rattus norvegicus
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.64 | 1.00 | 0.800 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 21070949 |
| Identification Methods | x-ray crystallography, fluorescence polarization spectroscopy, pull down, protein kinase assay, molecular sieving, isothermal titration calorimetry |
| Interaction Type | direct interaction, physical association, phosphorylation reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Pkinase~fn3, I-set~Pkinase |
| Common GO terms | GO:0005886 - plasma membrane GO:0006915 - apoptotic process GO:0030424 - axon |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
