Interactor 1: MK01 (P63086)
Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2)
Gene: Mapk1

Interactor 2: CDC37 (Q63692)
Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37) [Cleaved into: Hsp90 co-chaperone Cdc37, N-terminally processed]
Gene: CDC37

Species: Rattus norvegicus

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 30053369
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CDC37_M~Pkinase, CDC37_N~Pkinase
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0019901 - protein kinase binding
GO:0031435 - mitogen-activated protein kinase kinase kinase binding
GO:0032991 - protein-containing complex
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 358
Rn

1 379
+ Rn
+ Hs
+ Rn
+ Mm
+ Hs
+ Sp
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024