HitPredict

Interactor 1: PP1G (P63087)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: Ppp1cc

Interactor 2: B2CL1 (Q64373)
Bcl-2-like protein 1 (Bcl2-L-1) (Apoptosis regulator Bcl-X)
Gene: Bcl2l1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	17274640
Identification Methods	affinity chromatography technology, antibody array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0005741 - mitochondrial outer membrane GO:0007283 - spermatogenesis GO:0019901 - protein kinase binding GO:0044877 - protein-containing complex binding and 1 others more... GO:0098793 - presynapse
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 323 Mm			1 233
+	Hs
		737765 PP1G_HUMAN (1-323): 0: 601: 99.69		B2CL1_HUMAN (1-233): 4.44e-99: 289: 97.85
+	Hs
		905852 PP1A_HUMAN (1-323): 0: 578: 90.66		B2CL1_HUMAN (1-233): 4.44e-99: 289: 97.85
+	Mm
		489481 PP1G_MOUSE (1-323): 0: 601: 100.00		BCL2_MOUSE (5-231): 4.89e-74: 226: 41.45
+	Hs
		489378 PP1G_HUMAN (1-323): 0: 601: 99.69		BCL2_HUMAN (5-231): 1.03e-69: 215: 43.04
+	Mm
		489480 PP1A_MOUSE (1-323): 0: 578: 90.36		BCL2_MOUSE (5-231): 4.89e-74: 226: 41.45
+	Hs
		489393 PP1A_HUMAN (1-323): 0: 578: 90.66		BCL2_HUMAN (5-231): 1.03e-69: 215: 43.04
+	Hs
		489394 PP1B_HUMAN (1-322): 0: 559: 86.89		BCL2_HUMAN (5-231): 1.03e-69: 215: 43.04
+	Hs
		906060 PP1A_HUMAN (1-323): 0: 578: 90.66		B2CL2_HUMAN (39-231): 3.83e-58: 184: 42.49
+	Mm
		926536 PP1G_MOUSE (1-323): 0: 601: 100.00		BAX_MOUSE (31-198): 4.7e-45: 150: 23.39
+	Hs
		905851 PP1A_HUMAN (1-323): 0: 578: 90.66		BAX_HUMAN (31-198): 7.46e-48: 158: 22.22
+	Hs
		489398 PP2AA_HUMAN (8-312): 1.1e-177: 495: 46.08		BCL2_HUMAN (5-231): 1.03e-69: 215: 43.04