HitPredict

Interactor 1: PP1G (P63087)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: Ppp1cc

Interactor 2: MYPT1 (Q9DBR7)
Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1)
Gene: Ppp1r12a

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	22544752
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000776 - kinetochore GO:0005730 - nucleolus GO:0005737 - cytoplasm GO:0019901 - protein kinase binding GO:0046822 - regulation of nucleocytoplasmic transport and 1 others more... GO:0072357 - PTW/PP1 phosphatase complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 323 Mm			1 1029
+	Hs
		161322 PP1G_HUMAN (1-323): 0: 601: 99.69		MYPT1_HUMAN (1-1029): 1.44e-132: 428: 92.44
+	Mm
		906366 PP1A_MOUSE (1-323): 0: 578: 90.36		MYPT1_MOUSE (1-1029): 6.1e-134: 432: 100.00
+	Hs
		161347 PP1A_HUMAN (1-323): 0: 578: 90.66		MYPT1_HUMAN (1-1029): 1.44e-132: 428: 92.44
+	Hs
		161348 PP1B_HUMAN (1-322): 0: 559: 86.89		MYPT1_HUMAN (1-1029): 1.44e-132: 428: 92.44
+	Gg
		907234 PP1B_CHICK (1-322): 0: 559: 86.89		MYPT1_CHICK (1-984): 5.53e-102: 345: 82.39
+	Hs
		737978 PP1G_HUMAN (1-323): 0: 601: 99.69		PP16A_HUMAN (2-490): 9.32e-82: 277: 26.19
+	Hs
		906079 PP1A_HUMAN (1-323): 0: 578: 90.66		PP16A_HUMAN (2-490): 9.32e-82: 277: 26.19
+	Hs
		737999 PP1G_HUMAN (1-323): 0: 601: 99.69		PP16B_HUMAN (2-517): 7.62e-71: 248: 25.60
+	Hs
		906561 PP1B_HUMAN (1-322): 0: 559: 86.89		PP16A_HUMAN (2-490): 9.32e-82: 277: 26.19
+	Hs
		906099 PP1A_HUMAN (1-323): 0: 578: 90.66		PP16B_HUMAN (2-517): 7.62e-71: 248: 25.60
+	Hs
		3260 PP1B_HUMAN (1-322): 0: 559: 86.89		A0A0S2Z4Q8_HUMAN (2-163): 2.9e-61: 208: 64.91
+	Hs
		738024 PP1G_HUMAN (1-323): 0: 601: 99.69		PP12C_HUMAN (528-1029): 3.13e-32: 137: 23.23
+	Hs
		906116 PP1A_HUMAN (1-323): 0: 578: 90.66		PP12C_HUMAN (528-1029): 3.13e-32: 137: 23.23
+	Hs
		225129 PP1G_HUMAN (1-323): 0: 601: 99.69		MYPT2_HUMAN (1-894): 1.52e-22: 106: 10.20
+	Mm
		906252 PP1A_MOUSE (1-323): 0: 578: 90.36		PP12C_MOUSE (583-1029): 4.47e-29: 127: 24.03
+	Mm
		906293 PP1A_MOUSE (1-323): 0: 578: 90.36		MYPT2_MOUSE (1-887): 4.07e-23: 108: 11.80
+	Hs
		225132 PP1A_HUMAN (1-323): 0: 578: 90.66		MYPT2_HUMAN (1-894): 1.52e-22: 106: 10.20
+	Hs
		225133 PP1B_HUMAN (1-322): 0: 559: 86.89		MYPT2_HUMAN (1-894): 1.52e-22: 106: 10.20
+	Hs
		906000 PP1A_HUMAN (1-323): 0: 578: 90.66		PPR27_HUMAN (36-152): 1.42e-18: 85.5: 39.83
+	Hs
		906517 PP1B_HUMAN (1-322): 0: 559: 86.89		PPR27_HUMAN (36-152): 1.42e-18: 85.5: 39.83