Interactor 1: GNAS2 (P63092)
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short (Adenylate cyclase-stimulating G alpha protein)
Gene: GNAS

Interactor 2: GNA12 (Q03113)
Guanine nucleotide-binding protein subunit alpha-12 (G alpha-12) (G-protein subunit alpha-12)
Gene: GNA12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.847

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains G-alpha~G-alpha
Common GO terms GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005737 - cytoplasm
GO:0005834 - heterotrimeric G-protein complex
GO:0005886 - plasma membrane
and 2 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 394
Hs

1 381
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024