Interactor 1: GNAI1 (P63096)
Guanine nucleotide-binding protein G(i) subunit alpha-1 (Adenylate cyclase-inhibiting G alpha protein)
Gene: GNAI1

Interactor 2: PTH1R (Q03431)
Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH/PTHrP type I receptor) (PTH/PTHr receptor) (Parathyroid hormone 1 receptor) (PTH1 receptor)
Gene: PTH1R

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 16099817
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains 7tm_2~G-alpha
Common GO terms GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0007186 - G protein-coupled receptor signaling pathway
GO:0007188 - adenylate cyclase-modulating G protein-coupled receptor signaling pathway
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 354
Hs

1 593
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024