HitPredict

Interactor 1: 1433Z (P63101)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1) (SEZ-2)
Gene: Ywhaz

Interactor 2: ARG28 (P97433)
Rho guanine nucleotide exchange factor 28 (190 kDa guanine nucleotide exchange factor) (p190-RhoGEF) (p190RhoGEF) (Rho guanine nucleotide exchange factor) (Rho-interacting protein 2)
Gene: Arhgef28

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	11533041
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	14-3-3~C1_1
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Mm			1 1700
+	Mm
		910228 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		ARG28_MOUSE (1-1700): 0: 1350: 100.00
+	Hs
		927294 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		ARG28_HUMAN (1-1700): 0: 1322: 80.04
+	Hs
		909803 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		ARG28_HUMAN (1-1700): 0: 1322: 80.04
+	Hs
		927198 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		ARHGI_HUMAN (479-1659): 2.41e-118: 409: 35.07
+	Mm
		926797 1433Z_MOUSE (1-245): 3.48e-145: 407: 100.00		ARHG2_MOUSE (626-1604): 6.88e-120: 405: 33.00
+	Hs
		927379 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		ARHG2_HUMAN (626-1604): 4.27e-119: 402: 34.03
+	Hs
		909883 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		ARHG2_HUMAN (626-1604): 4.27e-119: 402: 34.03
+	Mm
		926817 1433Z_MOUSE (1-245): 3.48e-145: 407: 100.00		ARHGI_MOUSE (491-1659): 4.52e-113: 394: 34.64
+	Hs
		926978 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		AKP13_HUMAN (1-849): 1.72e-96: 349: 17.01
+	Hs
		909491 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		AKP13_HUMAN (1-849): 1.72e-96: 349: 17.01
+	Hs
		926988 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		TIAM1_HUMAN (515-1444): 1.46e-92: 334: 13.62
+	Hs
		909501 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		TIAM1_HUMAN (515-1444): 1.46e-92: 334: 13.62
+	Hs
		927201 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		FGD6_HUMAN (565-1345): 2.31e-92: 332: 13.57
+	Hs
		909717 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		FGD6_HUMAN (565-1345): 2.31e-92: 332: 13.57
+	Mm
		926773 1433Z_MOUSE (1-245): 3.48e-145: 407: 100.00		RGRF2_MOUSE (628-1503): 3.12e-84: 304: 14.10
+	Hs
		927416 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		SPT13_HUMAN (635-1260): 1.02e-73: 262: 12.99
+	Hs
		909921 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		SPT13_HUMAN (635-1260): 1.02e-73: 262: 12.99
+	Hs
		297127 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		PKHG5_HUMAN (825-1332): 1.75e-38: 159: 17.66
+	Hs
		297126 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		PKHG5_HUMAN (825-1332): 1.75e-38: 159: 17.66
+	Hs
		297119 1433T_HUMAN (1-245): 2.6e-140: 395: 80.00		PKHG5_HUMAN (825-1332): 1.75e-38: 159: 17.66