HitPredict

Interactor 1: 1433Z (P63101)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1) (SEZ-2)
Gene: Ywhaz

Interactor 2: PDE1B (Q01065)
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (Cam-PDE 1B) (EC 3.1.4.17) (63 kDa Cam-PDE)
Gene: PDE1B

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16959763
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0007165 - signal transduction
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 245 Mm			1 535
+	Mm
		926801 1433Z_MOUSE (1-245): 3.48e-145: 407: 100.00		PDE1A_MOUSE (4-518): 0: 689: 58.26
+	Hs
		872399 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		PDE1A_HUMAN (4-501): 0: 682: 59.31
+	Mm
		926778 1433Z_MOUSE (1-245): 3.48e-145: 407: 100.00		PDE4D_MOUSE (53-522): 1.11e-152: 456: 29.09
+	Hs
		927028 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		PDE7A_HUMAN (134-492): 3.77e-129: 387: 29.46
+	Hs
		909546 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		PDE7A_HUMAN (134-492): 3.77e-129: 387: 29.46
+	Hs
		683334 1433B_HUMAN (1-242): 9.01e-140: 393: 88.02		PDE7A_HUMAN (134-492): 3.77e-129: 387: 29.46
+	Hs
		927558 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		PDE7B_HUMAN (133-476): 9.23e-123: 369: 29.44
+	Hs
		910054 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		PDE7B_HUMAN (133-476): 9.23e-123: 369: 29.44
+	Hs
		647301 1433T_HUMAN (1-245): 2.6e-140: 395: 80.00		PDE7B_HUMAN (133-476): 9.23e-123: 369: 29.44
+	Hs
		683736 1433B_HUMAN (1-242): 9.01e-140: 393: 88.02		PDE7B_HUMAN (133-476): 9.23e-123: 369: 29.44
+	Hs
		905142 1433G_HUMAN (1-240): 8.4e-109: 315: 74.59		PDE7B_HUMAN (133-476): 9.23e-123: 369: 29.44
+	Hs
		927008 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		PDE3B_HUMAN (157-430): 8.24e-44: 168: 33.03
+	Hs
		927039 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		PDE3A_HUMAN (157-430): 1.22e-43: 168: 34.76
+	Hs
		909520 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		PDE3B_HUMAN (157-430): 8.24e-44: 168: 33.03
+	Hs
		646867 1433T_HUMAN (1-245): 2.6e-140: 395: 80.00		PDE3B_HUMAN (157-430): 8.24e-44: 168: 33.03
+	Hs
		646886 1433T_HUMAN (1-245): 2.6e-140: 395: 80.00		PDE3A_HUMAN (157-430): 1.22e-43: 168: 34.76
+	Hs
		904523 1433G_HUMAN (1-240): 8.4e-109: 315: 74.59		PDE3B_HUMAN (157-430): 8.24e-44: 168: 33.03
+	Hs
		981979 1433F_HUMAN (2-240): 5.21e-108: 313: 74.49		PDE3B_HUMAN (157-430): 8.24e-44: 168: 33.03