HitPredict

Interactor 1: 1433Z (P63101)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1) (SEZ-2)
Gene: Ywhaz

Interactor 2: KS6A5 (Q8C050)
Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 5) (Nuclear mitogen- and stress-activated protein kinase 1) (RSK-like protein kinase) (RLSK)
Gene: Rps6ka5

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20129940
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0006468 - protein phosphorylation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Mm			1 863
+	Hs
		270395 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		KS6A5_HUMAN (18-863): 0: 697: 84.75
+	Hs
		681776 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		AKT1_HUMAN (347-816): 5.28e-120: 373: 18.92
+	Hs
		681770 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		AKT1_HUMAN (347-816): 5.28e-120: 373: 18.92
+	Hs
		647354 1433T_HUMAN (1-245): 2.6e-140: 395: 80.00		KS6B2_HUMAN (487-849): 7e-118: 368: 20.42
+	At
		965291 14332_ARATH (3-239): 6.89e-143: 401: 65.15		CDPK1_ARATH (2-318): 1.38e-113: 361: 26.52
+	At
		802001 14334_ARATH (3-239): 1.97e-140: 396: 63.07		CDPK1_ARATH (2-318): 1.38e-113: 361: 26.52
+	Dm
		955037 1433E_DROME (2-242): 3.33e-143: 402: 66.67		Q9VR61_DROME (454-848): 4.14e-107: 353: 19.66
+	Hs
		646741 1433T_HUMAN (1-245): 2.6e-140: 395: 80.00		KS6A3_HUMAN (436-838): 4.15e-111: 358: 20.96
+	Hs
		646913 1433T_HUMAN (1-245): 2.6e-140: 395: 80.00		KS6A1_HUMAN (484-834): 8.86e-109: 352: 20.94
+	Hs
		568620 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		KAPCA_HUMAN (485-802): 1.19e-100: 318: 24.39
+	Hs
		568616 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		KAPCA_HUMAN (485-802): 1.19e-100: 318: 24.39
+	Hs
		610682 1433T_HUMAN (1-245): 2.6e-140: 395: 80.00		KAPCB_HUMAN (485-802): 6.67e-100: 316: 24.70
+	Hs
		909590 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		KS6A2_HUMAN (13-317): 4.28e-91: 305: 23.72
+	At
		788319 14331_ARATH (3-238): 4.25e-142: 400: 64.58		KPK1_ARATH (457-824): 8.84e-95: 307: 23.02
+	Dm
		664624 1433Z_DROME (1-245): 3.35e-143: 402: 81.63		Q94533_DROME (485-855): 1.32e-92: 302: 20.67
+	Hs
		272848 1433T_HUMAN (1-245): 2.6e-140: 395: 80.00		KS6A4_HUMAN (20-319): 1.29e-73: 258: 24.20
+	Hs
		272852 1433B_HUMAN (1-242): 9.01e-140: 393: 88.02		KS6A4_HUMAN (20-319): 1.29e-73: 258: 24.20
+	Hs
		783973 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		KPCI_HUMAN (559-740): 2.86e-18: 91.7: 30.89
+	Hs
		783970 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		KPCI_HUMAN (559-740): 2.86e-18: 91.7: 30.89
+	Hs
		646701 1433T_HUMAN (1-245): 2.6e-140: 395: 80.00		KPCI_HUMAN (559-740): 2.86e-18: 91.7: 30.89