HitPredict

Interactor 1: 1433Z (P63101)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1) (SEZ-2)
Gene: Ywhaz

Interactor 2: RPGF2 (Q8CHG7)
Rap guanine nucleotide exchange factor 2 (Cyclic nucleotide ras GEF) (CNrasGEF) (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF-1) (Ras/Rap1-associating GEF-1)
Gene: Rapgef2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16959763
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0019901 - protein kinase binding GO:0032991 - protein-containing complex GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Mm			1 1496
+	Hs
		927702 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		RPGF2_HUMAN (1-1496): 0: 1559: 94.53
+	Hs
		910200 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		RPGF2_HUMAN (1-1496): 0: 1559: 94.53
+	Hs
		647416 1433T_HUMAN (1-245): 2.6e-140: 395: 80.00		RPGF2_HUMAN (1-1496): 0: 1559: 94.53
+	Hs
		683851 1433B_HUMAN (1-242): 9.01e-140: 393: 88.02		RPGF2_HUMAN (1-1496): 0: 1559: 94.53
+	Hs
		927336 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		RPGF6_HUMAN (20-1496): 0: 1254: 62.87
+	Hs
		909851 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		RPGF6_HUMAN (20-1496): 0: 1254: 62.87
+	Hs
		647134 1433T_HUMAN (1-245): 2.6e-140: 395: 80.00		RPGF6_HUMAN (20-1496): 0: 1254: 62.87
+	Hs
		683569 1433B_HUMAN (1-242): 9.01e-140: 393: 88.02		RPGF6_HUMAN (20-1496): 0: 1254: 62.87
+	Hs
		683335 1433B_HUMAN (1-242): 9.01e-140: 393: 88.02		RGRF1_HUMAN (277-952): 8.31e-127: 429: 17.03
+	Hs
		647081 1433T_HUMAN (1-245): 2.6e-140: 395: 80.00		GRP3_HUMAN (633-1243): 1.23e-121: 398: 16.10
+	Hs
		927257 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		RGPS2_HUMAN (669-1217): 1.6e-116: 380: 15.95
+	Hs
		909770 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		RGPS2_HUMAN (669-1217): 1.6e-116: 380: 15.95
+	Hs
		647073 1433T_HUMAN (1-245): 2.6e-140: 395: 80.00		RGPS2_HUMAN (669-1217): 1.6e-116: 380: 15.95
+	Hs
		683515 1433B_HUMAN (1-242): 9.01e-140: 393: 88.02		RGPS2_HUMAN (669-1217): 1.6e-116: 380: 15.95
+	Hs
		904810 1433G_HUMAN (1-240): 8.4e-109: 315: 74.59		RGPS2_HUMAN (669-1217): 1.6e-116: 380: 15.95
+	Hs
		171544 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		RGL2_HUMAN (688-1059): 3.89e-74: 266: 17.58
+	Hs
		171537 1433T_HUMAN (1-245): 2.6e-140: 395: 80.00		RGL2_HUMAN (688-1059): 3.89e-74: 266: 17.58
+	Hs
		171538 1433B_HUMAN (1-242): 9.01e-140: 393: 88.02		RGL2_HUMAN (688-1059): 3.89e-74: 266: 17.58
+	Hs
		171542 1433G_HUMAN (1-240): 8.4e-109: 315: 74.59		RGL2_HUMAN (688-1059): 3.89e-74: 266: 17.58
+	Mm
		926773 1433Z_MOUSE (1-245): 3.48e-145: 407: 100.00		RGRF2_MOUSE (277-373): 1.08e-15: 85.1: 21.43