HitPredict

Interactor 1: 1433Z (P63101)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1) (SEZ-2)
Gene: Ywhaz

Interactor 2: ARHG7 (Q9ES28)
Rho guanine nucleotide exchange factor 7 (Beta-Pix) (PAK-interacting exchange factor beta) (p85SPR)
Gene: Arhgef7

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16959763
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0019901 - protein kinase binding GO:0032991 - protein-containing complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Mm			1 862
+	Hs
		909551 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		ARHG7_HUMAN (1-772): 0: 606: 91.68
+	Mm
		926851 1433Z_MOUSE (1-245): 3.48e-145: 407: 100.00		ARHG6_MOUSE (1-861): 4.26e-173: 521: 51.96
+	Hs
		927416 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		SPT13_HUMAN (66-638): 7.45e-97: 318: 19.71
+	Hs
		927568 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		ARHG4_HUMAN (107-638): 7.21e-96: 317: 22.38
+	Hs
		909921 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		SPT13_HUMAN (66-638): 7.45e-97: 318: 19.71
+	Hs
		910068 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		ARHG4_HUMAN (107-638): 7.21e-96: 317: 22.38
+	Hs
		927379 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		ARHG2_HUMAN (96-860): 1.16e-91: 312: 13.17
+	Hs
		909883 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		ARHG2_HUMAN (96-860): 1.16e-91: 312: 13.17
+	Mm
		926797 1433Z_MOUSE (1-245): 3.48e-145: 407: 100.00		ARHG2_MOUSE (96-860): 3.51e-89: 305: 13.17
+	Hs
		926978 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		AKP13_HUMAN (57-860): 5.96e-86: 303: 14.45
+	Hs
		909491 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		AKP13_HUMAN (57-860): 5.96e-86: 303: 14.45
+	Hs
		646842 1433T_HUMAN (1-245): 2.6e-140: 395: 80.00		AKP13_HUMAN (57-860): 5.96e-86: 303: 14.45
+	Hs
		50581 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		PKHG3_HUMAN (225-560): 3.1e-83: 292: 24.13
+	Hs
		50576 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		PKHG3_HUMAN (225-560): 3.1e-83: 292: 24.13
+	Mm
		926776 1433Z_MOUSE (1-245): 3.48e-145: 407: 100.00		ARG28_MOUSE (104-862): 7.7e-80: 284: 11.51
+	Mm
		926817 1433Z_MOUSE (1-245): 3.48e-145: 407: 100.00		ARHGI_MOUSE (214-854): 5.18e-79: 281: 14.27
+	Hs
		50558 1433T_HUMAN (1-245): 2.6e-140: 395: 80.00		PKHG3_HUMAN (225-560): 3.1e-83: 292: 24.13
+	Mm
		910228 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		ARG28_MOUSE (104-862): 7.7e-80: 284: 11.51
+	Hs
		926988 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		TIAM1_HUMAN (217-435): 6.56e-12: 71.6: 26.16
+	Hs
		909501 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		TIAM1_HUMAN (217-435): 6.56e-12: 71.6: 26.16