HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: SPTB2 (Q01082)
Spectrin beta chain, non-erythrocytic 1 (Beta-II spectrin) (Fodrin beta chain) (Spectrin, non-erythroid beta chain 1)
Gene: SPTBN1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	15161933
Identification Methods	pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0045296 - cadherin binding GO:0070062 - extracellular exosome and 1 others more... GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 2364
+	Mm
		926806 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		SPTB2_MOUSE (1-2364): 0: 742: 98.31
+	Hs
		211558 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		ACTN4_HUMAN (53-525): 6.51e-121: 409: 47.58
+	Hs
		211554 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		ACTN4_HUMAN (53-525): 6.51e-121: 409: 47.58
+	Hs
		926965 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		ACTN3_HUMAN (41-776): 4.93e-97: 338: 33.73
+	Hs
		360618 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		SPTA1_HUMAN (179-1394): 3.14e-92: 337: 19.60
+	Hs
		927475 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		CP250_HUMAN (220-2019): 1.07e-55: 218: 10.02
+	Hs
		909975 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		CP250_HUMAN (220-2019): 1.07e-55: 218: 10.02
+	Mm
		82753 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		B9EKJ1_MOUSE (266-1626): 1.35e-50: 201: 19.03
+	Hs
		297824 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		K0754_HUMAN (210-1343): 2.52e-36: 154: 15.07
+	Hs
		297821 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		K0754_HUMAN (210-1343): 2.52e-36: 154: 15.07
+	Mm
		434798 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		SPTA1_MOUSE (288-860): 3.62e-34: 147: 17.57
+	Hs
		926949 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		DYST_HUMAN (537-1421): 8.42e-22: 106: 12.00
+	Hs
		909464 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		DYST_HUMAN (537-1421): 8.42e-22: 106: 12.00
+	Hs
		927025 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		SPTN1_HUMAN (152-1087): 9.93e-19: 96.3: 16.89
+	Hs
		909544 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		SPTN1_HUMAN (152-1087): 9.93e-19: 96.3: 16.89
+	Mm
		926889 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		PLEC_MOUSE (222-1030): 9.76e-17: 89.7: 10.14
+	Hs
		927068 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		PLEC_HUMAN (222-1144): 1.08e-16: 89.7: 11.59
+	Hs
		927659 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		MACF1_HUMAN (687-1920): 4.98e-16: 87.6: 12.23
+	Hs
		910159 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		MACF1_HUMAN (687-1920): 4.98e-16: 87.6: 12.23
+	Mm
		926814 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		Q68FG2_MOUSE (1661-2338): 2.39e-10: 68.6: 14.96