HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: ACTN3 (Q08043)
Alpha-actinin-3 (Alpha-actinin skeletal muscle isoform 3) (F-actin cross-linking protein)
Gene: ACTN3

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	20618440
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0044325 - transmembrane transporter binding GO:0070062 - extracellular exosome
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 245 Hs			1 901
+	Hs
		725640 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		ACTN2_HUMAN (13-901): 0: 663: 79.98
+	Hs
		646682 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		ACTN2_HUMAN (13-901): 0: 663: 79.98
+	Hs
		211558 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		ACTN4_HUMAN (25-901): 0: 651: 74.26
+	Hs
		211554 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		ACTN4_HUMAN (25-901): 0: 651: 74.26
+	Hs
		521518 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		ACTN1_HUMAN (19-901): 0: 687: 77.82
+	Hs
		211551 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		ACTN4_HUMAN (25-901): 0: 651: 74.26
+	Mm
		926814 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		Q68FG2_MOUSE (257-768): 7.31e-12: 71.9: 12.48
+	Mm
		926806 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		SPTB2_MOUSE (257-791): 4.78e-11: 69.3: 10.45
+	Hs
		926931 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		SPTB2_HUMAN (227-791): 2.62e-11: 70: 10.78
+	Hs
		506805 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		SPTB1_HUMAN (173-841): 8.4e-10: 65: 10.41
+	Hs
		904449 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		SPTB2_HUMAN (227-791): 2.62e-11: 70: 10.78
+	Hs
		963298 1433F_HUMAN (2-240): 1.26e-107: 312: 74.49		SPTB2_HUMAN (227-791): 2.62e-11: 70: 10.78