HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: EIF3I (Q13347)
Eukaryotic translation initiation factor 3 subunit I (eIF3i) (Eukaryotic translation initiation factor 3 subunit 2) (TGF-beta receptor-interacting protein 1) (TRIP-1) (eIF-3-beta) (eIF3 p36)
Gene: EIF3I

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	36931259
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 245 Hs			1 325
+	Hs
		909518 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		EIF3I_HUMAN (1-325): 3.67e-93: 281: 100.00
+	Hs
		646865 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		EIF3I_HUMAN (1-325): 3.67e-93: 281: 100.00
+	Hs
		904521 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		EIF3I_HUMAN (1-325): 3.67e-93: 281: 100.00
+	Hs
		684015 1433S_HUMAN (1-237): 8.27e-104: 302: 71.97		EIF3I_HUMAN (1-325): 3.67e-93: 281: 100.00
+	Hs
		903106 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65
+	Hs
		927391 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		SNR40_HUMAN (3-122): 1.87e-26: 108: 20.93
+	Hs
		792963 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		LIS1_HUMAN (1-82): 2.95e-21: 95.1: 25.61
+	Hs
		792954 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		LIS1_HUMAN (1-82): 2.95e-21: 95.1: 25.61
+	Hs
		683188 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		LIS1_HUMAN (1-82): 2.95e-21: 95.1: 25.61
+	Hs
		927381 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		FBXW7_HUMAN (5-75): 4.23e-09: 59.6: 24.05
+	Hs
		909885 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		FBXW7_HUMAN (5-75): 4.23e-09: 59.6: 24.05
+	Hs
		647171 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		FBXW7_HUMAN (5-75): 4.23e-09: 59.6: 24.05
+	Hs
		683605 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		FBXW7_HUMAN (5-75): 4.23e-09: 59.6: 24.05
+	Mm
		935526 1433F_MOUSE (2-240): 1.16e-107: 312: 74.07		SNR40_MOUSE (3-122): 2.28e-26: 108: 20.93
+	Hs
		792950 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		LIS1_HUMAN (1-82): 2.95e-21: 95.1: 25.61
+	Hs
		792974 1433F_HUMAN (2-240): 1.26e-107: 312: 74.49		LIS1_HUMAN (1-82): 2.95e-21: 95.1: 25.61
+	Hs
		904953 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		FBXW7_HUMAN (5-75): 4.23e-09: 59.6: 24.05
+	Hs
		684254 1433S_HUMAN (1-237): 8.27e-104: 302: 71.97		FBXW7_HUMAN (5-75): 4.23e-09: 59.6: 24.05