HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: SPTN1 (Q13813)
Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) (Spectrin, non-erythroid alpha subunit)
Gene: SPTAN1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	15161933
Identification Methods	pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0045296 - cadherin binding GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 2472
+	Hs
		909544 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		SPTN1_HUMAN (1-2472): 0: 714: 100.00
+	Mm
		82753 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		B9EKJ1_MOUSE (1-2472): 0: 706: 98.18
+	Mm
		434798 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		SPTA1_MOUSE (1-2472): 2.17e-161: 558: 54.20
+	Hs
		360618 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		SPTA1_HUMAN (1-2472): 2.98e-159: 552: 54.81
+	Mm
		926814 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		Q68FG2_MOUSE (141-1932): 3.76e-63: 242: 20.06
+	Hs
		297824 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		K0754_HUMAN (1-1482): 9.32e-58: 225: 14.65
+	Hs
		297821 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		K0754_HUMAN (1-1482): 9.32e-58: 225: 14.65
+	Hs
		926931 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		SPTB2_HUMAN (2-1043): 1.4e-42: 174: 20.52
+	Mm
		926889 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		PLEC_MOUSE (1-1250): 7.03e-38: 159: 10.80
+	Hs
		926949 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		DYST_HUMAN (5-2410): 1.41e-35: 152: 10.59
+	Hs
		909464 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		DYST_HUMAN (5-2410): 1.41e-35: 152: 10.59
+	Hs
		927068 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		PLEC_HUMAN (16-1253): 4.4e-31: 137: 9.18
+	Mm
		926806 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		SPTB2_MOUSE (1408-2420): 1.22e-29: 132: 18.86
+	Hs
		927659 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		MACF1_HUMAN (9-1261): 9.1e-18: 93.6: 12.48
+	Hs
		910159 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		MACF1_HUMAN (9-1261): 9.1e-18: 93.6: 12.48
+	Hs
		506805 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		SPTB1_HUMAN (1743-2409): 3.32e-13: 78.1: 19.70
+	Hs
		927475 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		CP250_HUMAN (1768-2439): 4.39e-10: 67.7: 8.94
+	Hs
		211558 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		ACTN4_HUMAN (1843-2219): 1.15e-09: 66.2: 20.15
+	Hs
		909975 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		CP250_HUMAN (1768-2439): 4.39e-10: 67.7: 8.94
+	Hs
		211554 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		ACTN4_HUMAN (1843-2219): 1.15e-09: 66.2: 20.15