HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: EIF3A (Q14152)
Eukaryotic translation initiation factor 3 subunit A (eIF3a) (Eukaryotic translation initiation factor 3 subunit 10) (eIF-3-theta) (eIF3 p167) (eIF3 p180) (eIF3 p185)
Gene: EIF3A

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.586

Property	Details
Experiments	20936779, 15161933
Identification Methods	two hybrid, pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 1382
+	Hs
		909549 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		EIF3A_HUMAN (1-1382): 3.42e-120: 410: 100.00
+	Mm
		926855 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		MYH9_MOUSE (55-1069): 2.38e-45: 182: 10.19
+	Hs
		724761 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		MYH9_HUMAN (55-1098): 6.44e-45: 180: 9.65
+	Hs
		646681 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		MYH9_HUMAN (55-1098): 6.44e-45: 180: 9.65
+	Mm
		926804 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		MYH10_MOUSE (55-1099): 1.67e-35: 150: 9.82
+	Hs
		725130 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		MYH10_HUMAN (46-929): 1.09e-34: 147: 10.53
+	Hs
		927644 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		MYH13_HUMAN (638-1382): 4.53e-29: 128: 8.77
+	Hs
		502907 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		MYH3_HUMAN (355-1375): 4.75e-28: 125: 9.20
+	Hs
		728466 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		MYH11_HUMAN (79-823): 1.69e-23: 110: 11.10
+	Hs
		927643 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		MYH2_HUMAN (36-853): 1.99e-23: 110: 10.32
+	Hs
		728460 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		MYH11_HUMAN (79-823): 1.69e-23: 110: 11.10
+	Hs
		646685 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		MYH11_HUMAN (79-823): 1.69e-23: 110: 11.10
+	Hs
		927068 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		PLEC_HUMAN (497-1343): 1.73e-18: 94.5: 13.97
+	Hs
		522602 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		MYH7_HUMAN (83-989): 5.61e-18: 92.8: 10.62
+	Hs
		927475 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		CP250_HUMAN (74-918): 1.12e-17: 92: 10.23
+	Hs
		909975 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		CP250_HUMAN (74-918): 1.12e-17: 92: 10.23
+	Hs
		522590 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		MYH7_HUMAN (83-989): 5.61e-18: 92.8: 10.62
+	Mm
		926889 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		PLEC_MOUSE (482-1061): 7.55e-13: 76.1: 15.79
+	Mm
		926886 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		MY18A_MOUSE (557-1270): 4.37e-11: 70.3: 12.15
+	Hs
		551660 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		DESP_HUMAN (478-1060): 3.57e-11: 70.4: 13.18