HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: PTN14 (Q15678)
Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez)
Gene: PTPN14

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.621

Property	Details
Experiments	36931259, 22948661
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 1187
+	Hs
		909595 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		PTN14_HUMAN (1-1187): 0: 985: 100.00
+	Hs
		646918 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		PTN14_HUMAN (1-1187): 0: 985: 100.00
+	Hs
		927093 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		PTN21_HUMAN (1-1187): 0: 817: 52.29
+	Hs
		909614 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		PTN21_HUMAN (1-1187): 0: 817: 52.29
+	Hs
		927524 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		E41L1_HUMAN (5-713): 7.06e-142: 453: 17.33
+	Hs
		910025 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		E41L1_HUMAN (5-713): 7.06e-142: 453: 17.33
+	Hs
		647274 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		E41L1_HUMAN (5-713): 7.06e-142: 453: 17.33
+	Hs
		577010 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		PTPRA_HUMAN (428-1181): 5.96e-139: 442: 18.42
+	Hs
		927682 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		E41L3_HUMAN (13-857): 2.64e-133: 435: 16.82
+	Hs
		910185 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		E41L3_HUMAN (13-857): 2.64e-133: 435: 16.82
+	Hs
		663973 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		PTN4_HUMAN (598-1183): 2.04e-126: 413: 23.38
+	Hs
		663970 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		PTN4_HUMAN (598-1183): 2.04e-126: 413: 23.38
+	Hs
		646653 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		PTN4_HUMAN (598-1183): 2.04e-126: 413: 23.38
+	Hs
		547003 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		EZRI_HUMAN (18-364): 4.84e-121: 387: 20.96
+	Hs
		640230 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		PTN3_HUMAN (3-879): 1.01e-90: 315: 15.76
+	Hs
		640229 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		PTN3_HUMAN (3-879): 1.01e-90: 315: 15.76
+	Hs
		640212 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		PTN3_HUMAN (3-879): 1.01e-90: 315: 15.76
+	Hs
		926984 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		PTN13_HUMAN (1-802): 3.94e-78: 286: 16.36
+	Hs
		909498 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		PTN13_HUMAN (1-802): 3.94e-78: 286: 16.36
+	Hs
		646848 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		PTN13_HUMAN (1-802): 3.94e-78: 286: 16.36