HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: F263 (Q16875)
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (6PF-2-K/Fru-2,6-P2ase 3) (PFK/FBPase 3) (6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme) (Renal carcinoma antigen NY-REN-56) (iPFK-2) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)]
Gene: PFKFB3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	33961781, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 245 Hs			1 520
+	Hs
		646933 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		F263_HUMAN (1-520): 0: 805: 100.00
+	Hs
		683382 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		F263_HUMAN (1-520): 0: 805: 100.00
+	Hs
		904618 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		F263_HUMAN (1-520): 0: 805: 100.00
+	Hs
		982053 1433F_HUMAN (2-240): 1.26e-107: 312: 74.49		F263_HUMAN (1-520): 0: 805: 100.00
+	Hs
		241685 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		F262_HUMAN (29-475): 0: 655: 74.17
+	Hs
		241684 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		F262_HUMAN (29-475): 0: 655: 74.17
+	Hs
		927096 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		F264_HUMAN (2-455): 0: 649: 69.96
+	Hs
		909615 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		F264_HUMAN (2-455): 0: 649: 69.96
+	Hs
		241678 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		F262_HUMAN (29-475): 0: 655: 74.17
+	Hs
		241679 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		F262_HUMAN (29-475): 0: 655: 74.17
+	Hs
		646934 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		F264_HUMAN (2-455): 0: 649: 69.96
+	Hs
		683383 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		F264_HUMAN (2-455): 0: 649: 69.96
+	Hs
		241683 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		F262_HUMAN (29-475): 0: 655: 74.17
+	Hs
		241688 1433F_HUMAN (2-240): 1.26e-107: 312: 74.49		F262_HUMAN (29-475): 0: 655: 74.17
+	Hs
		904619 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		F264_HUMAN (2-455): 0: 649: 69.96
+	Hs
		982054 1433F_HUMAN (2-240): 1.26e-107: 312: 74.49		F264_HUMAN (2-455): 0: 649: 69.96
+	Hs
		578306 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		PGAM1_HUMAN (244-442): 5.92e-72: 231: 20.88
+	Mm
		910294 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		PGAM5_MOUSE (215-426): 3.77e-53: 183: 16.51