HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: SH319 (Q5HYK7)
SH3 domain-containing protein 19 (ADAM-binding protein Eve-1) (EEN-binding protein) (EBP)
Gene: SH3D19

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35271311, 36931259
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 790
+	Hs
		909634 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		SH319_HUMAN (1-790): 3.57e-99: 327: 100.00
+	Hs
		646951 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		SH319_HUMAN (1-790): 3.57e-99: 327: 100.00
+	Mm
		910242 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		SRBS2_MOUSE (634-788): 1.16e-31: 135: 29.45
+	Hs
		909849 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		SH3R3_HUMAN (418-723): 9.67e-28: 122: 17.33
+	Hs
		924450 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		GRB2_HUMAN (498-718): 1.8e-24: 104: 20.27
+	Hs
		909427 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		GRB2_HUMAN (498-718): 1.8e-24: 104: 20.27
+	Hs
		646781 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		GRB2_HUMAN (498-718): 1.8e-24: 104: 20.27
+	Dm
		664604 1433Z_DROME (1-245): 3.35e-143: 402: 81.22		GRAP_DROME (498-720): 2.27e-21: 95.2: 22.22
+	Dm
		954994 1433E_DROME (2-242): 3.33e-143: 402: 66.67		GRAP_DROME (498-720): 2.27e-21: 95.2: 22.22
+	Hs
		927191 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		DNMBP_HUMAN (492-785): 3.4e-16: 85.6: 17.22
+	Hs
		909706 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		DNMBP_HUMAN (492-785): 3.4e-16: 85.6: 17.22
+	Hs
		298968 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		SRBS2_HUMAN (612-787): 2.26e-15: 82.6: 22.53
+	Hs
		275184 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		GRAP2_HUMAN (305-554): 1.65e-16: 83.6: 15.20
+	Hs
		298967 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		SRBS2_HUMAN (612-787): 2.26e-15: 82.6: 22.53
+	Hs
		299007 V9HW98_HUMAN (2-241): 9.9e-144: 403: 68.18		SRBS2_HUMAN (612-787): 2.26e-15: 82.6: 22.53
+	Hs
		298950 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		SRBS2_HUMAN (612-787): 2.26e-15: 82.6: 22.53
+	Hs
		927227 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		SH3R1_HUMAN (244-550): 1.54e-09: 63.7: 11.61
+	Hs
		927478 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		SRBS1_HUMAN (672-788): 2.98e-09: 62.8: 33.07
+	Hs
		909744 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		SH3R1_HUMAN (244-550): 1.54e-09: 63.7: 11.61
+	Hs
		909979 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		SRBS1_HUMAN (672-788): 2.98e-09: 62.8: 33.07