HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: RPGP2 (Q684P5)
Rap1 GTPase-activating protein 2 (Rap1GAP2) (GTPase-activating Rap/Ran-GAP domain-like protein 4)
Gene: RAP1GAP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	20936779
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 730
+	Hs
		909669 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		RPGP2_HUMAN (1-730): 0: 1085: 100.00
+	Hs
		812876 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		RPGP1_HUMAN (62-694): 0: 758: 52.50
+	Hs
		812874 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		RPGP1_HUMAN (62-694): 0: 758: 52.50
+	Hs
		927611 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		SI1L2_HUMAN (151-474): 8.57e-136: 440: 37.68
+	Hs
		910116 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		SI1L2_HUMAN (151-474): 8.57e-136: 440: 37.68
+	Hs
		927396 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		SIPA1_HUMAN (123-550): 1.5e-135: 427: 33.56
+	Hs
		196429 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		SI1L1_HUMAN (151-472): 1.24e-128: 421: 38.01
+	Hs
		196427 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		SI1L1_HUMAN (151-472): 1.24e-128: 421: 38.01
+	Hs
		196402 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		SI1L1_HUMAN (151-472): 1.24e-128: 421: 38.01
+	Hs
		230235 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		SI1L3_HUMAN (107-472): 3.71e-125: 411: 36.60
+	Hs
		230231 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		SI1L3_HUMAN (107-472): 3.71e-125: 411: 36.60
+	Hs
		927166 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		RGPA1_HUMAN (178-486): 1.22e-101: 345: 23.08
+	Hs
		909678 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		RGPA1_HUMAN (178-486): 1.22e-101: 345: 23.08
+	Dm
		114591 1433Z_DROME (1-245): 3.35e-143: 402: 81.22		M9PD17_DROME (242-540): 2.84e-72: 259: 22.44
+	Dm
		114606 1433E_DROME (2-242): 3.33e-143: 402: 66.67		M9PD17_DROME (242-540): 2.84e-72: 259: 22.44
+	Dm
		664663 1433Z_DROME (1-245): 3.35e-143: 402: 81.22		Q9VW83_DROME (242-540): 2.84e-72: 259: 22.44
+	Dm
		955043 1433E_DROME (2-242): 3.33e-143: 402: 66.67		Q9VW83_DROME (242-540): 2.84e-72: 259: 22.44
+	Hs
		835039 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		TSC2_HUMAN (233-530): 1.44e-65: 238: 20.71
+	Hs
		835035 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		TSC2_HUMAN (233-530): 1.44e-65: 238: 20.71
+	Mm
		926787 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		Q3TQ10_MOUSE (292-411): 7.14e-44: 160: 28.57