HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: RICTR (Q6R327)
Rapamycin-insensitive companion of mTOR (AVO3 homolog) (hAVO3)
Gene: RICTOR

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.88	0.60	0.727

Property	Details
Experiments	33961781, 35271311, 36931259, 37120454, 28514442, 19720745
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0019901 - protein kinase binding GO:0043066 - negative regulation of apoptotic process
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 245 Hs			1 1708
+	Hs
		909697 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		647014 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		683461 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		904731 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		982159 1433F_HUMAN (2-240): 1.26e-107: 312: 74.49		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		684134 1433S_HUMAN (1-237): 8.27e-104: 302: 71.97		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Dm
		664664 1433Z_DROME (1-245): 3.35e-143: 402: 81.22		Q9VWJ6_DROME (1566-1694): 2.64e-11: 71.3: 34.62
+	Dm
		955044 1433E_DROME (2-242): 3.33e-143: 402: 66.67		Q9VWJ6_DROME (1566-1694): 2.64e-11: 71.3: 34.62