HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: MPRIP (Q6WCQ1)
Myosin phosphatase Rho-interacting protein (M-RIP) (Rho-interacting protein 3) (RIP3) (p116Rip)
Gene: MPRIP

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.712

Property	Details
Experiments	33961781, 35271311, 36931259, 28514442, 15161933
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0045296 - cadherin binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 1025
+	Hs
		909703 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		MPRIP_HUMAN (1-1025): 9.29e-127: 412: 100.00
+	Mm
		910229 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		MPRIP_MOUSE (1-1024): 9.38e-118: 388: 88.01
+	Hs
		927332 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		DLG5_HUMAN (647-1019): 8.88e-54: 207: 21.61
+	Hs
		909845 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		DLG5_HUMAN (647-1019): 8.88e-54: 207: 21.61
+	Hs
		927164 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		MRCKG_HUMAN (599-998): 1.13e-44: 178: 19.48
+	Hs
		927168 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51
+	Hs
		909680 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51
+	Hs
		927545 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		PKHA5_HUMAN (318-1019): 7.56e-36: 149: 13.24
+	Hs
		910040 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		PKHA5_HUMAN (318-1019): 7.56e-36: 149: 13.24
+	Mm
		926855 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		MYH9_MOUSE (542-1025): 4.68e-18: 92.5: 8.68
+	Hs
		724761 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66
+	Hs
		927643 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		MYH2_HUMAN (122-873): 5.69e-17: 89: 9.31
+	Hs
		522602 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		MYH7_HUMAN (101-931): 7.33e-17: 88.6: 10.36
+	Mm
		926804 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		MYH10_MOUSE (534-1014): 8.31e-16: 85.1: 9.18
+	Hs
		725130 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		MYH10_HUMAN (534-1014): 3.94e-16: 85.9: 9.18
+	Hs
		522590 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		MYH7_HUMAN (101-931): 7.33e-17: 88.6: 10.36
+	Hs
		728466 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		MYH11_HUMAN (124-786): 1.25e-12: 74.7: 11.57
+	Mm
		926889 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		PLEC_MOUSE (494-979): 2.14e-11: 70.8: 14.60
+	Hs
		728460 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		MYH11_HUMAN (124-786): 1.25e-12: 74.7: 11.57
+	Hs
		927068 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		PLEC_HUMAN (499-978): 3.1e-11: 70.1: 14.96