HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: RFIP1 (Q6WKZ4)
Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein)
Gene: RAB11FIP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	28514442, 36931259
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 1283
+	Hs
		909704 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		RFIP1_HUMAN (1-1283): 1.26e-166: 533: 100.00
+	Hs
		927423 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		NED4L_HUMAN (20-621): 1.55e-64: 240: 12.03
+	Hs
		909930 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		NED4L_HUMAN (20-621): 1.55e-64: 240: 12.03
+	Mm
		910302 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		NED4L_MOUSE (20-621): 1.22e-63: 238: 12.01
+	Rn
		910358 1433E_RAT (2-241): 9.9e-144: 403: 68.18		NEDD4_RAT (20-411): 2.7e-51: 198: 13.22
+	Mm
		808343 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		NEDD4_MOUSE (20-397): 1.73e-48: 189: 14.95
+	Hs
		927218 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		RFIP2_HUMAN (12-463): 2.57e-46: 177: 34.79
+	Hs
		909736 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		RFIP2_HUMAN (12-463): 2.57e-46: 177: 34.79
+	Mm
		926854 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		RFIP5_MOUSE (1061-1278): 4.18e-41: 163: 26.19
+	Hs
		927480 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		RFIP5_HUMAN (1075-1278): 5.6e-39: 157: 23.87
+	Hs
		909981 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		RFIP5_HUMAN (1075-1278): 5.6e-39: 157: 23.87
+	Mm
		103331 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		RFIP2_MOUSE (12-463): 4.77e-39: 155: 33.92
+	Hs
		566348 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		KPCA_HUMAN (19-174): 1.99e-37: 152: 20.59
+	Hs
		566293 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		KPCA_HUMAN (19-174): 1.99e-37: 152: 20.59
+	Dm
		955045 1433E_DROME (2-242): 3.33e-143: 402: 66.67		Q9VWS3_DROME (14-696): 3.42e-32: 138: 17.63
+	Mm
		926842 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		Q8C8C0_MOUSE (20-176): 3.27e-23: 108: 24.84
+	Hs
		297824 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		K0754_HUMAN (342-935): 5.92e-16: 86: 12.86
+	Hs
		297821 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		K0754_HUMAN (342-935): 5.92e-16: 86: 12.86
+	Hs
		926936 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		ANK2_HUMAN (161-762): 1.11e-09: 65.4: 16.59
+	Hs
		909455 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		ANK2_HUMAN (161-762): 1.11e-09: 65.4: 16.59