HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: FGD6 (Q6ZV73)
FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24)
Gene: FGD6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.60	0.635

Property	Details
Experiments	35271311, 36931259
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 1430
+	Hs
		909717 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		FGD6_HUMAN (1-1430): 0: 1161: 100.00
+	Hs
		909711 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		FGD5_HUMAN (9-1430): 5.62e-126: 429: 25.48
+	Hs
		164691 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		MAST4_HUMAN (11-845): 1.53e-105: 374: 13.93
+	Hs
		164690 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		MAST4_HUMAN (11-845): 1.53e-105: 374: 13.93
+	Hs
		506568 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		BCR_HUMAN (337-1239): 7.6e-102: 356: 14.44
+	Hs
		506563 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		BCR_HUMAN (337-1239): 7.6e-102: 356: 14.44
+	Hs
		927294 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		ARG28_HUMAN (310-1227): 8.64e-91: 327: 14.58
+	Hs
		909803 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		ARG28_HUMAN (310-1227): 8.64e-91: 327: 14.58
+	Mm
		926818 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		BCR_MOUSE (337-1239): 3.01e-90: 322: 14.26
+	Hs
		927568 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		ARHG4_HUMAN (598-1242): 1.09e-91: 314: 14.50
+	Mm
		926776 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		ARG28_MOUSE (409-1227): 9.88e-86: 311: 13.94
+	Mm
		910228 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		ARG28_MOUSE (409-1227): 9.88e-86: 311: 13.94
+	Hs
		927416 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		SPT13_HUMAN (649-1227): 3.99e-89: 305: 14.62
+	Hs
		50581 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		PKHG3_HUMAN (810-1230): 5.16e-78: 285: 21.18
+	Mm
		926817 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		ARHGI_MOUSE (399-1191): 4.62e-77: 283: 14.54
+	Hs
		50576 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		PKHG3_HUMAN (810-1230): 5.16e-78: 285: 21.18
+	Mm
		926797 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		ARHG2_MOUSE (629-1214): 3.3e-76: 276: 15.39
+	Hs
		926975 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		ARHG5_HUMAN (640-1226): 9.96e-73: 270: 14.26
+	Hs
		927539 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		ECT2_HUMAN (808-1189): 1.24e-74: 270: 22.28
+	Hs
		909489 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		ARHG5_HUMAN (640-1226): 9.96e-73: 270: 14.26