HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: RFIP2 (Q7L804)
Rab11 family-interacting protein 2 (Rab11-FIP2) (NRip11)
Gene: RAB11FIP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.716

Property	Details
Experiments	26496610, 33961781, 35271311, 36931259, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0019901 - protein kinase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 512
+	Hs
		909736 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		RFIP2_HUMAN (1-512): 1.78e-156: 457: 100.00
+	Mm
		103331 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		RFIP2_MOUSE (1-512): 1.83e-153: 449: 93.36
+	Hs
		647045 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		RFIP2_HUMAN (1-512): 1.78e-156: 457: 100.00
+	Hs
		647296 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		SMUF1_HUMAN (2-461): 2.27e-67: 232: 12.40
+	Hs
		566348 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		KPCA_HUMAN (14-226): 8.32e-45: 169: 14.54
+	Hs
		566293 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		KPCA_HUMAN (14-226): 8.32e-45: 169: 14.54
+	Hs
		397155 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		KPCG_HUMAN (15-226): 3.11e-38: 150: 16.22
+	Dm
		955045 1433E_DROME (2-242): 3.33e-143: 402: 66.67		Q9VWS3_DROME (10-173): 6.11e-38: 150: 41.32
+	Mm
		926854 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		RFIP5_MOUSE (143-504): 1.46e-32: 133: 16.84
+	Hs
		927480 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		RFIP5_HUMAN (141-504): 7.27e-33: 134: 16.41
+	Hs
		909981 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		RFIP5_HUMAN (141-504): 7.27e-33: 134: 16.41
+	Hs
		927190 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		RFIP1_HUMAN (125-508): 9.75e-30: 126: 18.49
+	Hs
		909704 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		RFIP1_HUMAN (125-508): 9.75e-30: 126: 18.49
+	Hs
		647022 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		RFIP1_HUMAN (125-508): 9.75e-30: 126: 18.49
+	Hs
		683468 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		RFIP1_HUMAN (125-508): 9.75e-30: 126: 18.49
+	Mm
		926842 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		Q8C8C0_MOUSE (14-231): 4.9e-21: 98.7: 18.39
+	Hs
		48275 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		ESYT2_HUMAN (1-122): 2.96e-17: 87.4: 20.93
+	Hs
		927239 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		RIMS1_HUMAN (13-127): 8.22e-13: 73.5: 23.77
+	Hs
		909754 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		RIMS1_HUMAN (13-127): 8.22e-13: 73.5: 23.77
+	Hs
		647061 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		RIMS1_HUMAN (13-127): 8.22e-13: 73.5: 23.77