HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: K2C1B (Q7Z794)
Keratin, type II cytoskeletal 1b (Cytokeratin-1B) (CK-1B) (Keratin-77) (K77) (Type-II keratin Kb39)
Gene: KRT77

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	36931259, 34825085
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 578
+	Hs
		380563 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		K2C1_HUMAN (129-510): 2.95e-163: 481: 68.06
+	Hs
		409047 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		K2C8_HUMAN (136-521): 2.3e-135: 404: 55.70
+	Hs
		409044 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		K2C8_HUMAN (136-521): 2.3e-135: 404: 55.70
+	Hs
		409008 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		K2C8_HUMAN (136-521): 2.3e-135: 404: 55.70
+	Hs
		409014 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		K2C8_HUMAN (136-521): 2.3e-135: 404: 55.70
+	Hs
		380568 1433S_HUMAN (1-237): 8.27e-104: 302: 71.97		K2C1_HUMAN (129-510): 2.95e-163: 481: 68.06
+	Hs
		927293 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		K2C78_HUMAN (88-523): 1e-117: 360: 50.89
+	Hs
		409042 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		K2C8_HUMAN (136-521): 2.3e-135: 404: 55.70
+	Hs
		409055 1433F_HUMAN (2-240): 1.26e-107: 312: 74.49		K2C8_HUMAN (136-521): 2.3e-135: 404: 55.70
+	Hs
		409015 1433S_HUMAN (1-237): 8.27e-104: 302: 71.97		K2C8_HUMAN (136-521): 2.3e-135: 404: 55.70
+	Hs
		380460 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		K2C6B_HUMAN (3-496): 3.98e-82: 269: 58.38
+	Hs
		982264 1433F_HUMAN (2-240): 1.26e-107: 312: 74.49		K2C78_HUMAN (88-523): 1e-117: 360: 50.89
+	Hs
		909746 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		K2C1B_HUMAN (1-578): 3.81e-74: 249: 100.00
+	Mm
		910243 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		K22O_MOUSE (1-504): 3.95e-74: 249: 54.51
+	Hs
		683500 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		K2C1B_HUMAN (1-578): 3.81e-74: 249: 100.00
+	Hs
		904437 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		KRT85_HUMAN (39-485): 6.33e-88: 282: 43.11
+	Hs
		905163 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		KRT82_HUMAN (47-559): 8.9e-84: 272: 40.16
+	Hs
		904786 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		K2C1B_HUMAN (1-578): 3.81e-74: 249: 100.00
+	Hs
		982214 1433F_HUMAN (2-240): 1.26e-107: 312: 74.49		K2C1B_HUMAN (1-578): 3.81e-74: 249: 100.00
+	Hs
		904944 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		KRT35_HUMAN (48-477): 1.17e-64: 220: 23.20