HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: GCN1 (Q92616)
Stalled ribosome sensor GCN1 (GCN1 eIF-2-alpha kinase activator homolog) (GCN1-like protein 1) (General control of amino-acid synthesis 1-like protein 1) (Translational activator GCN1) (HsGCN1)
Gene: GCN1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	15161933
Identification Methods	pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0045296 - cadherin binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 245 Hs			1 2671
+	Hs
		647159 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		GCN1_HUMAN (1-2671): 0: 2129: 100.00
+	Hs
		268664 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		SF3B1_HUMAN (1238-2069): 1.02e-61: 236: 13.97
+	Hs
		268651 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		SF3B1_HUMAN (1238-2069): 1.02e-61: 236: 13.97
+	Hs
		927378 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		TNPO1_HUMAN (908-1705): 1.2e-50: 198: 13.59
+	Hs
		787451 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		MTOR_HUMAN (824-2632): 3.31e-34: 147: 12.46
+	Hs
		268647 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		SF3B1_HUMAN (1238-2069): 1.02e-61: 236: 13.97
+	Hs
		787440 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		MTOR_HUMAN (824-2632): 3.31e-34: 147: 12.46
+	Hs
		646705 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		MTOR_HUMAN (824-2632): 3.31e-34: 147: 12.46
+	Hs
		683184 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		MTOR_HUMAN (824-2632): 3.31e-34: 147: 12.46
+	Hs
		927249 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		CAND1_HUMAN (1460-2587): 2.11e-22: 108: 13.92
+	Hs
		909761 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		CAND1_HUMAN (1460-2587): 2.11e-22: 108: 13.92
+	Mm
		926823 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		2AAA_MOUSE (959-1405): 1.24e-19: 97.8: 12.22
+	Hs
		672007 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		2AAA_HUMAN (959-1405): 1.51e-19: 97.8: 12.22
+	Hs
		787438 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		MTOR_HUMAN (824-2632): 3.31e-34: 147: 12.46
+	Hs
		787460 1433F_HUMAN (2-240): 1.26e-107: 312: 74.49		MTOR_HUMAN (824-2632): 3.31e-34: 147: 12.46
+	Hs
		683882 1433S_HUMAN (1-237): 8.27e-104: 302: 71.97		MTOR_HUMAN (824-2632): 3.31e-34: 147: 12.46
+	Hs
		672068 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		2AAA_HUMAN (959-1405): 1.51e-19: 97.8: 12.22
+	Hs
		904545 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		CKAP5_HUMAN (953-1968): 8.99e-11: 70.1: 10.33
+	Hs
		981997 1433F_HUMAN (2-240): 1.26e-107: 312: 74.49		CKAP5_HUMAN (953-1968): 8.99e-11: 70.1: 10.33