HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: CEP63 (Q96MT8)
Centrosomal protein of 63 kDa (Cep63)
Gene: CEP63

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35709258
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0045824 - negative regulation of innate immune response
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 703
+	Hs
		927605 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		DAPLE_HUMAN (37-586): 4.1e-41: 164: 17.08
+	Hs
		910111 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		DAPLE_HUMAN (37-586): 4.1e-41: 164: 17.08
+	Hs
		926974 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		CGNL1_HUMAN (13-703): 9.98e-30: 128: 12.01
+	Hs
		909488 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		CGNL1_HUMAN (13-703): 9.98e-30: 128: 12.01
+	Hs
		728466 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		MYH11_HUMAN (1-585): 5.28e-26: 116: 10.94
+	Hs
		728460 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		MYH11_HUMAN (1-585): 5.28e-26: 116: 10.94
+	Hs
		725130 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		MYH10_HUMAN (145-703): 1.35e-24: 112: 10.78
+	Mm
		926804 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		MYH10_MOUSE (153-702): 3.31e-23: 107: 12.57
+	Mm
		926855 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		MYH9_MOUSE (1-520): 1.09e-21: 102: 11.22
+	Hs
		724761 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		MYH9_HUMAN (1-520): 3.09e-20: 98.3: 12.02
+	Hs
		927105 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		GRDN_HUMAN (150-697): 6.94e-17: 87.5: 12.91
+	Hs
		909625 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		GRDN_HUMAN (150-697): 6.94e-17: 87.5: 12.91
+	Mm
		926886 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		MY18A_MOUSE (51-573): 5.66e-15: 81.2: 13.17
+	Hs
		502907 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		MYH3_HUMAN (1-450): 1.24e-13: 76.9: 12.17
+	Hs
		927643 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		MYH2_HUMAN (305-702): 2.56e-13: 75.9: 11.98
+	Hs
		927644 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		MYH13_HUMAN (314-702): 5.42e-12: 71.7: 14.00
+	Hs
		927475 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		CP250_HUMAN (150-696): 7.75e-10: 64.8: 11.94
+	Hs
		522602 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		MYH7_HUMAN (367-695): 1.25e-09: 64: 10.00
+	Hs
		909975 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		CP250_HUMAN (150-696): 7.75e-10: 64.8: 11.94
+	Mm
		93548 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		DESP_MOUSE (59-550): 4.18e-09: 62.5: 18.91