HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: FRMD6 (Q96NE9)
FERM domain-containing protein 6 (Willin)
Gene: FRMD6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

Property	Details
Experiments	33961781, 36931259, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 622
+	Hs
		909922 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		FRMD6_HUMAN (1-622): 1.67e-171: 503: 100.00
+	Hs
		926984 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		PTN13_HUMAN (14-401): 8.49e-120: 394: 24.49
+	Hs
		909498 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		PTN13_HUMAN (14-401): 8.49e-120: 394: 24.49
+	Hs
		663973 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		PTN4_HUMAN (4-536): 8.69e-120: 379: 14.29
+	Hs
		663970 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		PTN4_HUMAN (4-536): 8.69e-120: 379: 14.29
+	Hs
		927524 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		E41L1_HUMAN (18-573): 2.35e-114: 364: 15.00
+	Hs
		910025 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		E41L1_HUMAN (18-573): 2.35e-114: 364: 15.00
+	Hs
		927682 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		E41L3_HUMAN (13-569): 1.1e-111: 361: 13.81
+	Hs
		927698 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		TLN1_HUMAN (1-593): 3.24e-108: 360: 12.68
+	Hs
		547003 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		EZRI_HUMAN (12-593): 3.93e-115: 357: 16.10
+	Hs
		505612 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		EPB41_HUMAN (14-572): 1.19e-110: 353: 14.83
+	Hs
		640086 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		MOES_HUMAN (12-595): 1.26e-110: 345: 15.20
+	Hs
		204648 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		E41L2_HUMAN (13-545): 1.19e-105: 343: 12.70
+	Hs
		204644 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		E41L2_HUMAN (13-545): 1.19e-105: 343: 12.70
+	Hs
		640230 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		PTN3_HUMAN (5-547): 9.8e-102: 331: 14.19
+	Hs
		640229 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		PTN3_HUMAN (5-547): 9.8e-102: 331: 14.19
+	Mm
		910287 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		FRM4A_MOUSE (12-334): 6.2e-85: 288: 19.64
+	Mm
		910323 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		FRM4B_MOUSE (12-379): 1.15e-74: 260: 19.06
+	Hs
		927076 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		PTN14_HUMAN (20-336): 1.44e-73: 258: 19.75
+	Hs
		909595 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		PTN14_HUMAN (20-336): 1.44e-73: 258: 19.75