HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: SYGP1 (Q96PV0)
Ras/Rap GTPase-activating protein SynGAP (Neuronal RasGAP) (Synaptic Ras GTPase-activating protein 1) (Synaptic Ras-GAP 1)
Gene: SYNGAP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 1343
+	Mm
		99950 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		SYGP1_MOUSE (1-1343): 0: 1003: 98.88
+	Hs
		909931 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		SYGP1_HUMAN (1-1343): 0: 1004: 100.00
+	Mm
		99940 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		SYGP1_MOUSE (1-1343): 0: 1003: 98.88
+	Hs
		647202 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		SYGP1_HUMAN (1-1343): 0: 1004: 100.00
+	Hs
		927150 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		DAB2P_HUMAN (97-1342): 0: 779: 46.78
+	Hs
		909664 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		DAB2P_HUMAN (97-1342): 0: 779: 46.78
+	Hs
		646987 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		DAB2P_HUMAN (97-1342): 0: 779: 46.78
+	Hs
		927633 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		NGAP_HUMAN (84-1341): 0: 732: 42.62
+	Hs
		910133 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		NGAP_HUMAN (84-1341): 0: 732: 42.62
+	Hs
		809256 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		IQGA1_HUMAN (219-857): 5.95e-123: 421: 13.21
+	Hs
		927058 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		GAPD1_HUMAN (412-1051): 3.01e-122: 417: 13.70
+	Hs
		909576 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		GAPD1_HUMAN (412-1051): 3.01e-122: 417: 13.70
+	Hs
		646715 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		IQGA1_HUMAN (219-857): 5.95e-123: 421: 13.21
+	Hs
		927262 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		RASL3_HUMAN (182-865): 4.68e-111: 376: 35.91
+	Hs
		909774 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		RASL3_HUMAN (182-865): 4.68e-111: 376: 35.91
+	Mm
		926782 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		NF1_MOUSE (408-712): 4.15e-82: 300: 23.51
+	Hs
		598458 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		NF1_HUMAN (408-712): 3.21e-82: 301: 23.21
+	Hs
		598455 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		NF1_HUMAN (408-712): 3.21e-82: 301: 23.21
+	Mm
		910233 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		NF1_MOUSE (408-712): 4.15e-82: 300: 23.51
+	Hs
		598427 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		NF1_HUMAN (408-712): 3.21e-82: 301: 23.21