HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: SRSF8 (Q9BRL6)
Serine/arginine-rich splicing factor 8 (Pre-mRNA-splicing factor SRP46) (Splicing factor SRp46) (Splicing factor, arginine/serine-rich 2B)
Gene: SRSF8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 245 Hs			1 282
+	Hs
		909453 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		SRSF2_HUMAN (1-100): 1.3e-41: 144: 80.00
+	Hs
		927658 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		PPIE_HUMAN (16-102): 3.36e-32: 122: 35.63
+	Hs
		910157 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		PPIE_HUMAN (16-102): 3.36e-32: 122: 35.63
+	Dm
		664631 1433Z_DROME (1-245): 3.35e-143: 402: 81.22		Q9V3T8_DROME (5-181): 7.07e-31: 115: 50.83
+	Hs
		683812 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		PPIE_HUMAN (16-102): 3.36e-32: 122: 35.63
+	Hs
		927003 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		PABP4_HUMAN (2-103): 9.14e-22: 96.7: 19.61
+	Hs
		909516 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		PABP4_HUMAN (2-103): 9.14e-22: 96.7: 19.61
+	Hs
		516444 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		PABP1_HUMAN (2-103): 1.99e-20: 92.9: 18.63
+	Hs
		646864 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		PABP4_HUMAN (2-103): 9.14e-22: 96.7: 19.61
+	Hs
		683319 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		PABP4_HUMAN (2-103): 9.14e-22: 96.7: 19.61
+	Hs
		905054 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		SRSF8_HUMAN (1-282): 5.34e-41: 144: 100.00
+	Hs
		982436 1433F_HUMAN (2-240): 1.26e-107: 312: 74.49		SRSF8_HUMAN (1-282): 5.34e-41: 144: 100.00
+	Hs
		683970 1433S_HUMAN (1-237): 8.27e-104: 302: 71.97		SRSF2_HUMAN (1-100): 1.3e-41: 144: 80.00
+	Hs
		684297 1433S_HUMAN (1-237): 8.27e-104: 302: 71.97		SRSF8_HUMAN (1-282): 5.34e-41: 144: 100.00
+	Hs
		905260 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		PPIE_HUMAN (16-102): 3.36e-32: 122: 35.63
+	Hs
		684394 1433S_HUMAN (1-237): 8.27e-104: 302: 71.97		PPIE_HUMAN (16-102): 3.36e-32: 122: 35.63
+	Hs
		516440 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		PABP1_HUMAN (2-103): 1.99e-20: 92.9: 18.63
+	Mm
		892746 1433F_MOUSE (2-240): 1.16e-107: 312: 74.07		CIRBP_MOUSE (16-168): 1.6e-20: 88: 33.33
+	Hs
		516374 1433S_HUMAN (1-237): 8.27e-104: 302: 71.97		PABP1_HUMAN (2-103): 1.99e-20: 92.9: 18.63