HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: PANK2 (Q9BZ23)
Pantothenate kinase 2, mitochondrial (hPanK2) (EC 2.7.1.33) (Pantothenic acid kinase 2) [Cleaved into: Pantothenate kinase 2, mitochondrial intermediate form (iPanK2); Pantothenate kinase 2, mitochondrial mature form (mPanK2)]
Gene: PANK2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35271311, 15161933
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001525 - angiogenesis GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 245 Hs			1 570
+	Hs
		909992 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		PANK2_HUMAN (1-570): 0: 916: 100.00
+	Hs
		647245 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		PANK2_HUMAN (1-570): 0: 916: 100.00
+	Hs
		683684 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		PANK2_HUMAN (1-570): 0: 916: 100.00
+	Hs
		905076 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		PANK2_HUMAN (1-570): 0: 916: 100.00
+	Hs
		982456 1433F_HUMAN (2-240): 1.26e-107: 312: 74.49		PANK2_HUMAN (1-570): 0: 916: 100.00
+	Hs
		927334 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		PANK1_HUMAN (86-569): 0: 548: 62.83
+	Hs
		647131 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		PANK1_HUMAN (86-569): 0: 548: 62.83
+	Hs
		647287 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		PANK3_HUMAN (207-566): 0: 539: 83.89
+	Hs
		683721 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		PANK3_HUMAN (207-566): 0: 539: 83.89
+	At
		965311 14332_ARATH (3-239): 6.89e-143: 401: 65.15		PANK2_ARATH (147-568): 1.32e-172: 513: 31.40
+	At
		788571 14333_ARATH (3-239): 1.48e-141: 398: 64.73		PANK2_ARATH (147-568): 1.32e-172: 513: 31.40
+	Hs
		905125 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		PANK3_HUMAN (207-566): 0: 539: 83.89
+	Hs
		982512 1433F_HUMAN (2-240): 1.26e-107: 312: 74.49		PANK3_HUMAN (207-566): 0: 539: 83.89