HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: TANC1 (Q9C0D5)
Protein TANC1 (Tetratricopeptide repeat, ankyrin repeat and coiled-coil domain-containing protein 1)
Gene: TANC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.51	0.60	0.554

Property	Details
Experiments	36931259
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 1861
+	Hs
		909999 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		TANC1_HUMAN (1-1861): 0: 1674: 100.00
+	Hs
		647254 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		TANC1_HUMAN (1-1861): 0: 1674: 100.00
+	Mm
		57379 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		A2AM57_MOUSE (752-1838): 9.85e-119: 405: 15.13
+	Hs
		926936 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		ANK2_HUMAN (832-1445): 1.76e-99: 360: 19.88
+	Hs
		909455 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		ANK2_HUMAN (832-1445): 1.76e-99: 360: 19.88
+	Hs
		646808 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		ANK2_HUMAN (832-1445): 1.76e-99: 360: 19.88
+	Mm
		56842 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		TANC2_MOUSE (789-1861): 1.25e-75: 282: 15.81
+	Mm
		56841 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		TANC2_MOUSE (789-1861): 1.25e-75: 282: 15.81
+	Hs
		927552 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		TANC2_HUMAN (813-1861): 1.46e-72: 272: 15.17
+	Hs
		910048 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		TANC2_HUMAN (813-1861): 1.46e-72: 272: 15.17
+	Hs
		647294 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		TANC2_HUMAN (813-1861): 1.46e-72: 272: 15.17
+	Hs
		257597 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		ANR17_HUMAN (1067-1308): 5.75e-51: 201: 28.46
+	Hs
		257595 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		ANR17_HUMAN (1067-1308): 5.75e-51: 201: 28.46
+	Hs
		257566 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		ANR17_HUMAN (1067-1308): 5.75e-51: 201: 28.46
+	Hs
		257572 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		ANR17_HUMAN (1067-1308): 5.75e-51: 201: 28.46
+	Hs
		909789 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		ANKH1_HUMAN (828-1073): 7.75e-39: 162: 17.34
+	Hs
		883471 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		RIPK4_HUMAN (629-935): 1.98e-34: 145: 12.14
+	Hs
		883468 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		RIPK4_HUMAN (629-935): 1.98e-34: 145: 12.14
+	Hs
		646759 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		RIPK4_HUMAN (629-935): 1.98e-34: 145: 12.14
+	Hs
		646746 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		DAPK1_HUMAN (1137-1270): 4.08e-10: 67.4: 32.09