HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: KLC2 (Q9H0B6)
Kinesin light chain 2 (KLC 2)
Gene: KLC2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.60	0.734

Property	Details
Experiments	33961781, 35271311, 36931259, 28514442, 15161933, 15324660
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, pull down, coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0045296 - cadherin binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 622
+	Hs
		910010 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		KLC2_HUMAN (1-622): 1.59e-128: 393: 100.00
+	Hs
		647263 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		KLC2_HUMAN (1-622): 1.59e-128: 393: 100.00
+	Hs
		927575 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		KLC4_HUMAN (7-618): 1.11e-105: 334: 69.13
+	Hs
		910078 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		KLC4_HUMAN (7-618): 1.11e-105: 334: 69.13
+	Hs
		647317 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		KLC4_HUMAN (7-618): 1.11e-105: 334: 69.13
+	Mm
		910337 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		KLC4_MOUSE (7-618): 1.34e-101: 323: 67.69
+	Hs
		174785 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		OGT1_HUMAN (58-526): 3.14e-51: 192: 16.63
+	Hs
		174775 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		OGT1_HUMAN (58-526): 3.14e-51: 192: 16.63
+	Mm
		910304 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		OGT1_MOUSE (58-526): 2.65e-51: 192: 16.63
+	Hs
		174660 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		OGT1_HUMAN (58-526): 3.14e-51: 192: 16.63
+	At
		788447 14331_ARATH (3-238): 4.25e-142: 400: 64.58		SEC_ARATH (4-455): 2.1e-38: 154: 16.15
+	Hs
		927384 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		TTC28_HUMAN (203-568): 1.33e-20: 99: 11.03
+	Hs
		909889 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		TTC28_HUMAN (203-568): 1.33e-20: 99: 11.03
+	Hs
		647173 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		TTC28_HUMAN (203-568): 1.33e-20: 99: 11.03
+	Hs
		927177 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		KLC3_HUMAN (363-616): 1.47e-16: 84.7: 21.78
+	Hs
		909688 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		KLC3_HUMAN (363-616): 1.47e-16: 84.7: 21.78
+	Hs
		647010 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		KLC3_HUMAN (363-616): 1.47e-16: 84.7: 21.78
+	Hs
		926963 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		KLC1_HUMAN (406-586): 8.56e-10: 63.5: 12.50
+	Hs
		909475 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		KLC1_HUMAN (406-586): 8.56e-10: 63.5: 12.50
+	Hs
		646831 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		KLC1_HUMAN (406-586): 8.56e-10: 63.5: 12.50