HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: MTMR4 (Q9NYA4)
Myotubularin-related protein 4 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 2) (FYVE-DSP2) (Zinc finger FYVE domain-containing protein 11)
Gene: MTMR4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	27432908, 28675297, 36931259
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 1195
+	Hs
		910087 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		MTMR4_HUMAN (1-1195): 0: 1246: 100.00
+	Hs
		647323 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		MTMR4_HUMAN (1-1195): 0: 1246: 100.00
+	Hs
		927016 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		MTMR3_HUMAN (1-1195): 0: 1019: 47.63
+	Hs
		909535 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		MTMR3_HUMAN (1-1195): 0: 1019: 47.63
+	Hs
		683328 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		MTMR3_HUMAN (1-1195): 0: 1019: 47.63
+	Mm
		926899 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		MTMR1_MOUSE (14-630): 0: 727: 28.37
+	Hs
		909534 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		MTMR2_HUMAN (7-630): 0: 716: 32.77
+	Mm
		926821 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		MTMR5_MOUSE (161-802): 7.58e-152: 501: 22.07
+	Hs
		309464 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		MTMR5_HUMAN (161-802): 8.65e-151: 499: 21.79
+	Hs
		927581 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		MTMRA_HUMAN (6-625): 2.53e-157: 490: 19.89
+	Hs
		309444 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		MTMR5_HUMAN (161-802): 8.65e-151: 499: 21.79
+	Hs
		927499 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		MTMRC_HUMAN (6-550): 9.99e-132: 422: 18.87
+	Hs
		910000 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		MTMRC_HUMAN (6-550): 9.99e-132: 422: 18.87
+	Hs
		647255 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		MTMRC_HUMAN (6-550): 9.99e-132: 422: 18.87
+	Hs
		927201 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		FGD6_HUMAN (610-1195): 4.14e-79: 288: 14.93
+	Hs
		909717 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		FGD6_HUMAN (610-1195): 4.14e-79: 288: 14.93
+	Hs
		647028 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		FGD6_HUMAN (610-1195): 4.14e-79: 288: 14.93
+	Hs
		927439 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		RUFY1_HUMAN (974-1173): 7.3e-41: 163: 27.00
+	Hs
		909944 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		RUFY1_HUMAN (974-1173): 7.3e-41: 163: 27.00
+	Hs
		647212 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		RUFY1_HUMAN (974-1173): 7.3e-41: 163: 27.00