HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: RABX5 (Q9UJ41)
Rab5 GDP/GTP exchange factor (RAP1) (Rabaptin-5-associated exchange factor for Rab5) (Rabex-5)
Gene: RABGEF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.662

Property	Details
Experiments	33961781, 35271311, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 491
+	Hs
		647362 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		RABX5_HUMAN (1-491): 0: 563: 100.00
+	Hs
		683797 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		RABX5_HUMAN (1-491): 0: 563: 100.00
+	Hs
		108670 G9K388_HUMAN (3-243): 7.47e-159: 447: 67.90		RIN3_HUMAN (62-454): 1.24e-71: 247: 18.10
+	Hs
		927418 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		ANR27_HUMAN (123-435): 9.66e-78: 264: 18.83
+	Hs
		909924 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		ANR27_HUMAN (123-435): 9.66e-78: 264: 18.83
+	Hs
		927058 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		GAPD1_HUMAN (45-372): 3.76e-74: 256: 20.78
+	Hs
		909576 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		GAPD1_HUMAN (45-372): 3.76e-74: 256: 20.78
+	Hs
		87695 D0PNI1_HUMAN (1-245): 1.67e-144: 405: 100.00		RIN3_HUMAN (62-454): 1.24e-71: 247: 18.10
+	Hs
		927327 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		RIN3_HUMAN (62-454): 1.24e-71: 247: 18.10
+	Hs
		683356 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		GAPD1_HUMAN (45-372): 3.76e-74: 256: 20.78
+	Hs
		647127 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		RIN3_HUMAN (62-454): 1.24e-71: 247: 18.10
+	Hs
		683558 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		RIN3_HUMAN (62-454): 1.24e-71: 247: 18.10
+	Mm
		910298 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		VP9D1_MOUSE (49-374): 9.16e-62: 214: 17.49
+	Hs
		927023 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		RIN1_HUMAN (81-444): 7.83e-58: 206: 13.44
+	Mm
		926865 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		RIN1_MOUSE (59-444): 5.92e-57: 203: 14.29
+	Hs
		909542 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		RIN1_HUMAN (81-444): 7.83e-58: 206: 13.44
+	Mm
		910325 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		RIN1_MOUSE (59-444): 5.92e-57: 203: 14.29
+	Hs
		683332 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		RIN1_HUMAN (81-444): 7.83e-58: 206: 13.44
+	Mm
		1265722 1433B_MOUSE (1-242): 3.77e-128: 364: 87.19		RIN1_MOUSE (59-444): 5.92e-57: 203: 14.29
+	Hs
		904541 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		RIN1_HUMAN (81-444): 7.83e-58: 206: 13.44