HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: SYNP2 (Q9UMS6)
Synaptopodin-2 (Genethonin-2) (Myopodin)
Gene: SYNPO2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	20936779
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0005925 - focal adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 1093
+	Mm
		1265221 1433B_MOUSE (1-242): 3.77e-128: 364: 87.19		SYNP2_MOUSE (1-1093): 1.12e-90: 316: 78.36
+	Hs
		164691 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		MAST4_HUMAN (32-1083): 1.22e-35: 150: 11.93
+	Hs
		910065 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		PDLI7_HUMAN (5-276): 3.88e-38: 151: 20.96
+	Hs
		164690 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		MAST4_HUMAN (32-1083): 1.22e-35: 150: 11.93
+	Hs
		164682 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		MAST4_HUMAN (32-1083): 1.22e-35: 150: 11.93
+	Hs
		927299 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		SYNPO_HUMAN (348-1089): 3.97e-33: 140: 18.48
+	Hs
		164684 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		MAST4_HUMAN (32-1083): 1.22e-35: 150: 11.93
+	Hs
		683644 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		MAGI1_HUMAN (5-369): 2.81e-29: 128: 14.91
+	Hs
		297824 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		K0754_HUMAN (631-1092): 2.33e-23: 110: 11.99
+	Hs
		297821 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		K0754_HUMAN (631-1092): 2.33e-23: 110: 11.99
+	Hs
		927196 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		OTOG_HUMAN (481-1017): 5.4e-20: 99.1: 13.70
+	Hs
		297815 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		K0754_HUMAN (631-1092): 2.33e-23: 110: 11.99
+	Hs
		909712 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		OTOG_HUMAN (481-1017): 5.4e-20: 99.1: 13.70
+	Hs
		647025 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		OTOG_HUMAN (481-1017): 5.4e-20: 99.1: 13.70
+	Hs
		683472 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		OTOG_HUMAN (481-1017): 5.4e-20: 99.1: 13.70
+	Hs
		909543 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		SHRM2_HUMAN (82-1088): 5.35e-09: 62.8: 9.52
+	Hs
		164689 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		MAST4_HUMAN (32-1083): 1.22e-35: 150: 11.93
+	Hs
		904684 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		MAGI3_HUMAN (7-451): 2.62e-30: 132: 13.56
+	Hs
		904746 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		OTOG_HUMAN (481-1017): 5.4e-20: 99.1: 13.70
+	Hs
		904542 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		SHRM2_HUMAN (82-1088): 5.35e-09: 62.8: 9.52