HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: GAB2 (Q9UQC2)
GRB2-associated-binding protein 2 (GRB2-associated binder 2) (Growth factor receptor bound protein 2-associated protein 2) (pp100)
Gene: GAB2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.91	0.60	0.739

Property	Details
Experiments	31980649, 33961781, 35271311, 36931259, 28514442, unassigned2173, 19172738
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 676
+	Mm
		926790 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		Q3ZB59_MOUSE (1-676): 0: 714: 91.31
+	Mm
		926898 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		GAB2_MOUSE (1-676): 0: 714: 91.16
+	Mm
		910246 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		Q3ZB59_MOUSE (1-676): 0: 714: 91.31
+	Hs
		927011 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		GAB1_HUMAN (3-675): 0: 652: 37.36
+	Hs
		909527 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		GAB1_HUMAN (3-675): 0: 652: 37.36
+	Hs
		63199 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		A6NIW2_HUMAN (2-457): 1.02e-111: 372: 16.08
+	Hs
		927120 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		DOC11_HUMAN (2-457): 1.02e-111: 372: 16.08
+	Hs
		909638 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		DOC11_HUMAN (2-457): 1.02e-111: 372: 16.08
+	Hs
		927168 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		PKHA7_HUMAN (6-456): 1.7e-80: 278: 14.62
+	Hs
		909680 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		PKHA7_HUMAN (6-456): 1.7e-80: 278: 14.62
+	Hs
		927546 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		PKHA2_HUMAN (2-229): 1.67e-55: 197: 21.55
+	Hs
		927490 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		DOCK9_HUMAN (2-485): 1.15e-51: 196: 12.16
+	Hs
		909993 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		DOCK9_HUMAN (2-485): 1.15e-51: 196: 12.16
+	Hs
		927548 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		PKHA1_HUMAN (3-163): 2.62e-36: 142: 23.46
+	Hs
		927545 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		PKHA5_HUMAN (6-453): 3.24e-26: 117: 15.35
+	Hs
		910040 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		PKHA5_HUMAN (6-453): 3.24e-26: 117: 15.35
+	Hs
		927232 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		PHLB2_HUMAN (9-114): 2.45e-24: 111: 28.04
+	Hs
		909748 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		PHLB2_HUMAN (9-114): 2.45e-24: 111: 28.04
+	Hs
		927241 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		PHLB1_HUMAN (8-113): 8.34e-17: 87: 26.27
+	Hs
		909755 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		PHLB1_HUMAN (8-113): 8.34e-17: 87: 26.27