HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: SH2B3 (Q9UQQ2)
SH2B adapter protein 3 (Lymphocyte adapter protein) (Lymphocyte-specific adapter protein Lnk) (Signal transduction protein Lnk)
Gene: SH2B3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36578217
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 575
+	Hs
		910175 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		SH2B3_HUMAN (1-575): 4.13e-166: 486: 100.00
+	Hs
		924450 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		GRB2_HUMAN (307-547): 8.13e-46: 162: 12.86
+	Hs
		909427 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		GRB2_HUMAN (307-547): 8.13e-46: 162: 12.86
+	Hs
		646781 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		GRB2_HUMAN (307-547): 8.13e-46: 162: 12.86
+	Hs
		683253 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		GRB2_HUMAN (307-547): 8.13e-46: 162: 12.86
+	Hs
		782768 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		CSK_HUMAN (354-444): 2.06e-32: 131: 29.67
+	Hs
		782766 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		CSK_HUMAN (354-444): 2.06e-32: 131: 29.67
+	Hs
		666059 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		SHC1_HUMAN (350-453): 1.1e-29: 125: 34.62
+	Hs
		666056 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		SHC1_HUMAN (350-453): 1.1e-29: 125: 34.62
+	Hs
		683181 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		CSK_HUMAN (354-444): 2.06e-32: 131: 29.67
+	Hs
		788960 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		MATK_HUMAN (343-444): 6e-22: 101: 32.35
+	Mm
		140059 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		P85B_MOUSE (329-473): 6.89e-20: 95.9: 18.49
+	Hs
		129271 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		P85B_HUMAN (329-463): 2.73e-18: 90.9: 18.38
+	Hs
		129265 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		P85B_HUMAN (329-463): 2.73e-18: 90.9: 18.38
+	Gg
		94476 1433Z_CHICK (1-245): 7.65e-144: 403: 99.18		KSYK_CHICK (362-492): 2.55e-16: 84.2: 24.11
+	Gg
		94492 1433E_CHICK (2-241): 9.9e-144: 403: 68.18		KSYK_CHICK (362-492): 2.55e-16: 84.2: 24.11
+	Hs
		129204 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		P85B_HUMAN (329-463): 2.73e-18: 90.9: 18.38
+	Hs
		129216 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		P85B_HUMAN (329-463): 2.73e-18: 90.9: 18.38
+	Hs
		782764 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		CSK_HUMAN (354-444): 2.06e-32: 131: 29.67
+	Hs
		666055 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		SHC1_HUMAN (350-453): 1.1e-29: 125: 34.62