HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: LRCH1 (Q9Y2L9)
Leucine-rich repeat and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1) (Neuronal protein 81) (NP81)
Gene: LRCH1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 728
+	Hs
		910189 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		LRCH1_HUMAN (1-728): 3.4e-151: 459: 100.00
+	Mm
		910293 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		LRCH3_MOUSE (60-691): 7.12e-93: 307: 37.88
+	Zm
		22560 B6U284_MAIZE (1-241): 1.06e-142: 401: 63.27		A0A1D6I257_MAIZE (1-507): 3.4e-67: 241: 14.45
+	Hs
		927034 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		SCRIB_HUMAN (71-589): 1.5e-52: 199: 15.60
+	Hs
		646881 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		SCRIB_HUMAN (71-589): 1.5e-52: 199: 15.60
+	Hs
		683339 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		SCRIB_HUMAN (71-589): 1.5e-52: 199: 15.60
+	Hs
		927431 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		ERBIN_HUMAN (123-615): 2.73e-37: 152: 16.37
+	Hs
		909939 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		ERBIN_HUMAN (123-615): 2.73e-37: 152: 16.37
+	Hs
		647208 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		ERBIN_HUMAN (123-615): 2.73e-37: 152: 16.37
+	Hs
		683646 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		ERBIN_HUMAN (123-615): 2.73e-37: 152: 16.37
+	Hs
		904552 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		SCRIB_HUMAN (71-589): 1.5e-52: 199: 15.60
+	At
		965375 14332_ARATH (3-239): 6.89e-143: 401: 65.15		BRL2_ARATH (5-280): 2.02e-23: 108: 19.45
+	At
		788442 14331_ARATH (3-238): 4.25e-142: 400: 64.58		EMS1_ARATH (428-637): 7.33e-23: 106: 11.31
+	At
		788683 14333_ARATH (3-239): 1.48e-141: 398: 64.73		BRL2_ARATH (5-280): 2.02e-23: 108: 19.45
+	At
		788640 14333_ARATH (3-239): 1.48e-141: 398: 64.73		EMS1_ARATH (428-637): 7.33e-23: 106: 11.31
+	Hs
		910166 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		SHOC2_HUMAN (61-184): 7.76e-21: 99.1: 29.37
+	Mm
		910240 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		LRCH2_MOUSE (6-191): 2.11e-19: 95.2: 14.85
+	Hs
		683820 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		SHOC2_HUMAN (61-184): 7.76e-21: 99.1: 29.37
+	At
		965369 14332_ARATH (3-239): 6.89e-143: 401: 65.15		CLV1_ARATH (4-134): 9.08e-15: 80.5: 14.29
+	Hs
		904985 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		LRCH3_HUMAN (5-163): 5.58e-20: 97.1: 17.54